Case Center for Biomolecular Engineering- Instruments

We currently have the following instruments available through the Center for Biomolecular Engineering. Inquiries regarding training and use should be directed to Ryan Hall ( We are located on the 4th floor of the Wickenden building.

1. OLYMPUS FV1000 Confocal Microscope

The Olympus FV1000 confocal microscope delivers high resolution images necessary for the multi-dimensional observation of cell and tissue morphology. It has the following capabilities:

A. Excellent Precision, Sensitivity, and Stability to enable precise bright imaging with minimum photoxicity

  • Laser Compatiblity:

    • Diode Laser: 405 nm, 440 nm, 473 nm, 559 nm, 635 nm
    • Gas laser: 458 nm, 488 nm, 515 nm, 
  • Can be used with tissue culture dishes, slide chambers, microplates and glass slides for live cells and fixed specimen

B. Two versions of light detection systems

  • Spectral Based Detection
  • Filter Based Detection 

C. Simultaneous Laser Light Stimulation

  1. Applications:

    • Diffusion measurement and Molecular Interaction Analysis
    • Light Stimulation: FRAP/FLIP/Photoactivation/Photoconversion/Uncaging
    • Multi-Dimensional Time-Lapse 
    • 3D Mosaic Imaging
    • Multi-Color Imaging
    • 3D/4D Volume Rendering
    • Colocalization
    • FRET

2. Agilent 5800 ICP-OES

  • Elemental analysis in various conditions:

    • Gd, Mn, Fe in nanoparticles or in animal organs (for biodistribution)
    • Pb and Cd in consumer goods (toys, jewelry and clothing).
    • N/P/K, S/Ca/Mg in fertilizers
    • S, P, Ca, Mg, Na, and K in biodiesel
    • Major, minor and toxic elements in foods, beverages and agricultural samples
    • Elements in pharmaceuticals
    • Trace impurities in high purity Cu

3. ChemiDoc XRS+ System

The ChemiDoc XRS+ System  uses CCD  high resolution, high sensitivity technology  to support multiple detection methods  including:  

 1) Fluorescence

 2) Colorimetry

 3) Densitometry

 4) Chemiluminescence

 5) Chemifluorescence

The system accommodates a wide array of  samples (polyacrylamide gels to small  agarose gels, and various blots). The  system is ideal for PCR, purification, and electrophoresis systems, allowing for documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.          

4. Anton Paar Litesizer 500

Anton Paar Litesizer 500 has the capability to measure particle size, zeta potential, molecular mass and transmittance by light scattering technology.