| Title | Multiattribute probabilistic prostate elastic registration (MAPPER): Application to fusion of ultrasound and magnetic resonance imaging. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Sparks, R, Nicolas Bloch B, Feleppa E, Barratt D, Moses D, Ponsky L, Madabhushi A |
| Journal | Medical physics |
| Volume | 42 |
| Issue | 3 |
| Pagination | 1153 |
| Date Published | 03/2015 |
| ISSN | 0094-2405 |
| Abstract | Transrectal ultrasound (TRUS)-guided needle biopsy is the current gold standard for prostate cancer diagnosis. However, up to 40% of prostate cancer lesions appears isoechoic on TRUS. Hence, TRUS-guided biopsy has a high false negative rate for prostate cancer diagnosis. Magnetic resonance imaging (MRI) is better able to distinguish prostate cancer from benign tissue. However, MRI-guided biopsy requires special equipment and training and a longer procedure time. MRI-TRUS fusion, where MRI is acquired preoperatively and then aligned to TRUS, allows for advantages of both modalities to be leveraged during biopsy. MRI-TRUS-guided biopsy increases the yield of cancer positive biopsies. In this work, the authors present multiattribute probabilistic postate elastic registration (MAPPER) to align prostate MRI and TRUS imagery. |
| DOI | 10.1118/1.4905104 |
| PDF Link | http://engineering.case.edu/centers/ccipd/system/files/MAPPER.pdf |
| Alternate Journal | Med Phys |
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