Title | Computer-Aided Laser Dissection: A Microdissection Workflow Leveraging Image Analysis Tools. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Hipp, JD, Johann DJ, Chen Y, Madabhushi A, Monaco J, Cheng J, Rodriguez-Canales J, Stumpe MC, Riedlinger G, Rosenberg AZ, Hanson JC, Kunju LP, Emmert-Buck MR, Balis UJ, Tangrea MA |
Journal | Journal of pathology informatics |
Volume | 9 |
Pagination | 45 |
Date Published | 2018 |
ISSN | 2229-5089 |
Abstract | The development and application of new molecular diagnostic assays based on next-generation sequencing and proteomics require improved methodologies for procurement of target cells from histological sections. Laser microdissection can successfully isolate distinct cells from tissue specimens based on visual selection for many research and clinical applications. However, this can be a daunting task when a large number of cells are required for molecular analysis or when a sizeable number of specimens need to be evaluated. |
DOI | 10.4103/jpi.jpi_60_18 |
PDF Link | |
Alternate Journal | J Pathol Inform |
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