| Title | Association of Peritumoral Radiomics With Tumor Biology and Pathologic Response to Preoperative Targeted Therapy for HER2 (ERBB2)-Positive Breast Cancer. |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Braman, N, Prasanna P, Whitney J, Singh S, Beig N, Etesami M, Bates DDB, Gallagher K, Bloch NB, Vulchi M, Turk P, Bera K, Abraham J, Sikov WM, Somlo G, Harris LN, Gilmore H, Plecha D, Varadan V, Madabhushi A |
| Journal | JAMA network open |
| Volume | 2 |
| Issue | 4 |
| Pagination | e192561 |
| Date Published | 2019 04 05 |
| ISSN | 2574-3805 |
| Keywords | Adult, Biomarkers, Tumor, Breast Neoplasms, Female, Humans, Lymphocytes, Tumor-Infiltrating, magnetic resonance imaging, Middle Aged, Neoadjuvant Therapy, Preoperative Period, Radiometry, Receptor, ErbB-2, Retrospective Studies, Treatment Outcome |
| Abstract | There has been significant recent interest in understanding the utility of quantitative imaging to delineate breast cancer intrinsic biological factors and therapeutic response. No clinically accepted biomarkers are as yet available for estimation of response to human epidermal growth factor receptor 2 (currently known as ERBB2, but referred to as HER2 in this study)-targeted therapy in breast cancer. |
| DOI | 10.1001/jamanetworkopen.2019.2561 |
| PDF Link | |
| Alternate Journal | JAMA Netw Open |
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