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Innovations in Imaging

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Computerized image analysis can predict cancer outcomes

His talk titled, “Applying a Novel AI Approach to Concluded Clinical Trial Data to Predict Response to Cancer Immunotherapy ”, was part of the “Advancements in IO Imaging“  track held on February 24th. 

Members of the Center for Computational Imaging and Personalized Diagnostics presented at the Technical Workshop: Computer-Aided Diagnosis on February 17th of the Society of Photo-optical Instrumentation Engineers (SPIE) Medical Imaging conference. 

“Probabilistic atlases of post-treatment multi-parametric MRI scans reveal distinct hemispheric distribution of glioblastoma progression versus pseudo-progression”.

The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Anirban Sen Gupta, Ph.D., Full Professor, Department of Biomedical Engineering, Case Western Reserve University to its College of Fellows. 

Promise and Reality of the Brave New World.. His talk titled, “Pathomics for Precision Oncology”, will be held on March 7th, 2021, 8:00am - 8:30am EST. 

After receiving a nomination to The Pathologist’s 2020 Power List, Anant Madabhushi, PhD, will be speaking alongside other nominees during the virtual event on March 2.

Researchers discover biomarkers to identify lung cancer patients who could be made worse by same drugs that helps many others

“Predicting pathological complete response to neoadjuvant chemotherapy from baseline breast dynamic contrast enhanced magnetic resonance imaging (DCE-MRI)” and “Predicting response to immunotherapy using computer extracted features relating to spatial arrangement of tumor infiltrating lymphocytes in non-small cell lung cancer”.

For all the promise of AI-created precision medicines, observers say there’s a long way to go before they'll come to a drugstore near you. Anant Madabhushi, a biomedical engineering professor at Case Western Reserve University School of Medicine, said, "there is a lot of optimism but also a lot of hype" in the use of AI for precision medicine.

The Research Highlights collection showcases the breadth of work being done by primary investigators with the support of grants from the EGRP portfolio. 

Inspirata: Upcoming fireside chat on Digital Pathology Innovation, being held virtually on March 2nd, featuring The Pathologist’s 2020 Power List, including Case Western Reserve University's 
Anant Madabhushi.

These hybrid nanoparticle systems can be intravenously administered to enable targeted hemorrhage control in treating traumatic injuries, and can act as platelet surrogates when platelet products are unavailable for transfusion. 

In an article titled, “Case Researchers Studying AI Use In Targeting Cancer Treatment,” author Anna Huntsman interviews CCIPD Director, Anant Madabhushi, PhD, about his work in precision medicine and recently-launched research agreement with the pharmaceutical company Boehringer Ingelheim. This collaboration will explore uses of AI to better identify therapies that are more likely to work for a specific patient. 

In a January 6th interview with Bio Patrika, Rakesh Shiradkar, PhD, discusses his vision, goals, and current projects with the Center for Computational Imaging and Personalized Diagnostics. Shiradkar further discusses the impact the center’s research is having on society and what personalized diagnostics means to him.

In a December 10th Reuters Health press release appearing on Medscape titled, “MRI-Based Nomograms May Predict Lymph Node Metastasis, Survival in Early Breast Cancer," author Marilynn Larkin quotes Nathaniel Braman, PhD, CCIPD alumnus, regarding how a machine learning MRI radiomic signature tool could help guide clinicians’ treatment decisions.

Newswise — CLEVELAND, Ohio --Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease is to recur following surgical treatment for prostate cancer. 

Anant Madabhushi, PhD, discusses how AI can be used to efficiently allocate healthcare resources by predicting response to treatment for COVID-19 patients.

Case Western Reserve and partners local and global team up to better predict which patients with oral squamous cell carcinomas will need radiation or chemotherapy after surgery

The agreement is the third partnership in 2020 between the CCIPD and leading biopharmaceutical companies to advance artificial intelligence (AI) tools for disease diagnosis and prognosis, as well as predicting response to therapy. In April, the CCIPD entered into a contract with AstraZeneca and earlier in the year had inked a similar deal with Bristol-Myers Squibb Company.