Online Master's in Biomedical Engineering @ Case.edu
A Mighty Force - read full story

Primary Faculty

A. Bolu Ajiboye, Ph.D.

Development and control of brain-computer-interface (BCI) technologies for restoring function to individuals who have experienced severely debilitating injuries to the nervous system, such as spinal cord injury and stroke

 

Jay Alberts, Ph.D.

Cleveland Clinic Lerner Research Institute

Parkinson's disease; deep brain stimulation; forced exercise; assisted exercise; stroke; robotics; concussion assessment
 

James M. Anderson, M.D., Ph.D.

Blood and tissue/material interactions as they relate to implantable devices and biomaterials; The cellular and humoral responses to implanted materials

 

Suneel S. Apte, MBBS, DPhil

Cleveland Clinic Lerner Research Institute

Extracellular matrix; connective tissue; proteolysis; metalloproteinases; ADAMTS proteases; proteomics; morphogenesis; cardiovascular disorders; musculoskeletal disorders; birth defects; fetal-maternal medicine; eye disorders; neural tube defects; craniofacial development; smooth muscle; post-translational modification; connective tissue disorders; osteoarthritis; primary cilium.

James P. Basilion, Ph.D.

High resolution imaging of endogenous gene expression; definition of "molecular signatures" for imaging and treatment of cancer and other diseases; generating and utilizing genomic data to define informative targets; strategies for applying non-invasive imaging to drug development; and novel molecular imaging probes and paradigms

Jillian Beveridge, Ph.D.

Cleveland Clinic Lerner Research Institute

Joint biomechanics; joint injury and post-traumatic osteoarthritis; magnetic resonance imaging of connective tissues; anterior cruciate ligament; biplane videoradiography

Jeffrey R. Capadona, Ph.D.

To develop an understanding for how the neuroinflammatory response facilitates acute and long-term neural device performance.

 

Patrick Crago, Ph.D.

Control of neuroprostheses for restoration of motor function; neuromechanics; and modeling of neuromusculoskeletal systems


 

Margot Damaser, PhD

Cleveland Clinic Lerner Research Institute

Urinary incontinence; pelvic floor disorders; fecal incontinence; pelvic organ prolapse; peripheral nerve injury; stem cell; regenerative medicine; electrical stimulation; pressure measurement; neurotrophin; animal models; bladder function; urethra; vagina; urodynamics

Kathleen A. Derwin, Ph.D.

Cleveland Clinic Lerner Research Institute

Rotator cuff repair; abdominal wall repair; musculoskeletal soft tissue repair; ECM scaffolds; extracellular matrix; muscle fatty atrophy

Colin K. Drummond, Ph.D.

Professor and Assistant Chair; Healthcare information technology applications to support clinical decision-making; wearable analytics for human performance assessment; sports health clinical studies for primary data-based simulation and modeling.

Dominique M. Durand, Ph.D.

Neural engineering; neural interfacing; neural prostheses; computational neuroscience; neural dynamics; neuromodulation; neurophysiology and control of epilepsy

 

Steven Eppell, Ph.D.

Biomaterials; instrumentation; nanoscale structure-function analysis of orthopaedic biomaterials; and scanning probe microscopy and spectroscopy of skeletal tissues

 

Ahmet Erdemir, Ph.D.

Cleveland Clinic Lerner Research Institute

Biomechanics; tissue mechanics; musculoskeletal; movement; locomotion; modeling; simulation; computation; finite element analysis; optimization; multiscale analysis; simulation-based medicine

Stephen D. Fening, Ph.D.

Translational Research; Commercialization; Medical Devices; Orthopedics; Biomechanics; Pre-clinical and Clinical Research 

 

Aaron Fleischman, PhD

Cleveland Clinic Lerner Research Institute

Biosensors; cell detection; imaging; IVUS; intravascular ultrasound; MEMS; microfluidics; nanotechnology; ultrafiltration; ultrasonic transducer

Kiyotaka Fukamachi, M.D., Ph.D.

Cleveland Clinic Lerner Research Institute

Mechanical circulatory support; ventricular assist device (VAD); total artificial heart (TAH); cardiac function; pressure-volume loop; hemodynamics; heart failure; neurostimulation; mitral valve

Miklos Gratzl, Ph.D.

Biomedical sensing and diagnostics in vitro and in vivo; electrochemical and optical techniques; BioMEMS for cellular transport; cancer multi-drug resistance at the single cell level; and sliver sensor for multi-analyte patient monitoring
 

Kenneth J. Gustafson, Ph.D.

Neural engineering; neural prostheses; neurophysiology and neural control of genitourinary function; devices to restore genitourinary function; and functional neuromuscular stimulation

 

Linda M. Graham, M.D.

Cleveland Clinic Lerner Research Institute

Vascular grafts; endothelial cells; smooth muscle cells; oxidized lipids; canonical transient receptor potential (TRPC) channels; cell migration; collagen synthesis

Emily Graczyk, Ph.D.

Dr. Graczyk’s research aims to understand the neural coding of somatosensation and to restore and augment sensory capabilities through neural stimulation in humans. Dr. Graczyk’s lab combines clinical studies, computational neuroscience, cognitive neuroscience, and artificial intelligence to examine the perception and utilization of sensory information for translation to persons both with and without sensory deficits.  

Vincent C. Hascall, Ph.D.

Cleveland Clinic Lerner Research Institute

Hyaluronan in inflammation; asthma; diabetes; autophagy; hyperglycemia; connective tissue biology

Michael Jenkins, Ph.D.

Focuses on developing new technology and therapies for autonomic dysfunction, congenital heart defects, and opioid-induced disorders. Advancement categories: infrared neuromodulation, imaging, and drug development.
 

Efstathios (Stathis) Karathanasis, Ph.D.

Cancer nanotechnology; Pediatric nanomedicine; Therapeutics for brain tumors; Targeted treatments for metastatic disease; Multi-ligand nanoparticles; Precise targeting of disease; Contrast agents for MR, CT and nuclear imaging; Molecular imaging
 

Robert Kirsch, Ph.D.

Restoration of movement using neuroprostheses; neuroprosthesis control system design; natural control of human movements; biomechanics of movement; computer-based modeling; and system identification

 

Vijay Krishna, Ph.D.

Cleveland Clinic Lerner Research Institute

Light-nanomaterial interactions for biomedical applications; multifunctional nanomaterials for non-invasive image-guided cancer treatment; nanotherapeutics for prevention of cancer; novel, long-lasting sunscreens

Vinod Labhasetwar, Ph.D.

Cleveland Clinic Lerner Research Institute

Nanomedicine; nanoparticles; cancer metastasis; drug delivery; stroke; spinal cord injury, retinitis pigmentosa, peripheral artery disease
 

Xiaojuan Li, Ph.D.

Cleveland Clinic Lerner Research Institute

Magnetic resonance (MR) and MR spectroscopic imaging in musculoskeletal disorders; clinically oriented quantitative imaging; early detection of cartilage degeneration; marrow adiposity and osteoporosis; rheumatoid and osteoarthritis; joint injury; Program for Advanced Medical Imaging

Zheng-Rong Lu, Ph.D.

Drug delivery and molecular imaging; novel targeted imaging agents for molecular imaging; novel MRI contrast agents; image-guided therapy and drug delivery; polymeric drug delivery systems; multi-functional delivery systems for nucleic acids
 

Dan Ma, Ph.D.

Magnetic Resonance Imaging (MRI);  Magnetic Resonance Fingerprinting ; Quantitative MR; MR Acquisition and Modeling;Neuroimaging

 

Debra McGivney, Ph.D.

Magnetic resonance imaging, Magnetic resonance fingerprinting, Inverse problems, Mathematical modeling

 

Anant Madabhushi, Ph.D.

Quantitative image analysis; Multi-modal, multi-scale correlation of massive data sets for disease diagnostics, prognostics, theragnostics: cancer applications.

 

Paul D. Marasco, Ph.D.

Cleveland Clinic Lerner Research Institute

Sensory integration with prosthetic devices; amputee research; cognitive embodiment; visual-tactile integration; sensory neurophysiology; brain organization; neural plasticity; kinesthesia; diabetic sensory neuropathy

Edward V. Maytin, M.D., Ph.D.

Cleveland Clinic Lerner Research Institute

Skin cancer; photodynamic therapy; light therapy; wound healing; inflammation; fibrosis; extracellular matrix
 

Cameron McIntyre, Ph.D.

Chronic high-frequency electrical stimulation of subcortical brain structures-- or deep brain stimulation (DBS)-- and its applications as a therapy for neurological disorders.

 

Ronald J. Midura, Ph.D.

Cleveland Clinic Lerner Research Institute

Skeletal biology; bone formation; metabolic bone disease; fracture healing; microgravity; space medicine; mechanical unloading
 

Michael Moffitt, Ph.D.

Fundamental and translational neural engineering activities. Primary areas of interest are anodic stimulation, low-amplitude neuromodulation (e.g., sub-perception stimulation of peripheral nerve or spinal cord) and photobiomodulation effects on neural elements. Brings 16+ years of industry experience in the medical device field focused on Spinal Cord Stimulation (SCS) and Deep Brain Stimulation (DBS) systems.

J. Thomas Mortimer, Ph.D.

Development of an electronic textbook for Applied Neural Control and understanding the electron transfer processes occurring on platinum neural stimulating electrodes.
 

George F. Muschler, M.D.

Cleveland Clinic Lerner Research Institute

Stem cell; progenitor cell; bone; cartilage; arthritis; aging; osteoporosis; bone loss; fracture non-union; blood; bone marrow; regenerative medicine; tissue engineering; gender differences; cell therapy; cell processing; orthopaedics; orthopaedic surgery; rheumatology; rehabilitation; quality; clinical outcomes; joint replacement

P. Hunter Peckham, Ph.D.

Rehabilitation engineering in spinal cord injury; neural prostheses; and functional electrical stimulation and technology transfer

 

Ela Plow, Ph.D., P.T.

Cleveland Clinic Lerner Research Institute

Aging; brain; brain damage; brain plasticity; cancer-related fatigue; chemo brain; functional magnetic resonance imaging (fMRI); hemianopia (vision defect); motor control; motor imagery; motor learning; motor cortex; motor mapping of brain; noninvasive brain stimulation; spinal cord injury; stroke; transcranial direct current stimulation; transcranial magnetic stimulation; neuroimaging; neuromodulation; neurorehabilitation; visual cortex; visual field loss

Andrew Rollins, Ph.D.

Biomedical optics; real-time in-vivo microstructural, functional, and molecular imaging using optical coherence tomography; diagnosis and guided therapy for cancer, cardiovascular, and ophthalmic disease

 

Carl Saab, Ph.D.

Cleveland Clinic Lerner Research Institute

Saab is the director of the Pain Science Technology And Research (STAR) Lab. Their research is based on emerging scientific findings showing that pain is mediated by brain activity, so their main goal is to define the brain networks mediating pain.

Gerald Saidel, Ph.D.

Mass and heat transport and metabolism in cells, tissues, and organ systems; mathematical modeling and simulation of dynamic and spatially distributed systems; optimal nonlinear parameter estimation and design of experiments

 

Anirban Sen Gupta, Ph.D.

Targeted drug delivery; targeted molecular imaging; image-guided therapy; platelet substitutes; novel polymeric biomaterials for tissue engineering scaffolds

 

Sam Senyo, Ph.D.

The Senyo Laboratory seeks to elucidate factors that regulate basal tissue injury response and early development to devise effective strategies for therapeutic regeneration, particularly in the heart. We approach this goal at several levels by integrating information derived from cross-disciplinary techniques of molecular biology, biophysics, polymer chemistry and biomimicry.

Andrew Shoffstall, Ph.D.

Development of minimally invasive neural interfaces for lower risk, lower cost, and higher impact applications in bioelectronic medicine and neural prostheses; other areas of interest include neuroanatomy and physiology, biomaterials, drug delivery, and inflammation.

 

Pallavi Tiwari, Ph.D.

Computerized decision support methods for evaluating disease presence and treatment response of radiotherapy and laser ablation therapy for neurological applications: brain tumors, epilepsy, and cancer pain. Novel automated algorithms to analyze and integrate multi-modal imaging data for disease diagnosis, prognosis, and treatment evaluation.

Ronald Triolo, Ph.D.

Restore/ or enhance the upright and seated mobility, posture and balance in individuals with neuro-musculo-skeletal disorders.

 

Dustin Tyler, Ph.D.

Sensory restoration; human-machine symbiosis; neuromimetic neuroprostheses; laryngeal neuroprostheses; clinical implementation of nerve electrodes; cortical neuroprostheses; minimally invasive implantation techniques; and modeling of neural stimulation and neuroprostheses
 

Geoffrey Vince, Ph.D.

Cleveland Clinic Lerner Research Institute

Cardiovascular imaging; stroke; histology; image and signal processing; atherosclerosis

Satish Viswanath, Ph.D.

Medical image analysis, image radiomics, and machine learning schemes, focused on the use of post-processing, co-registration, and biological quantitation of imaging data. Applications in image-guided interventions, predictive guidance, and quantitative treatment response characterization in gastrointestinal cancers and inflammatory diseases.

Horst von Recum, Ph.D.

Affinity-based delivery of small molecule drugs and biomolecules for applications in device infection, HIV, orthopedics, cardiovascular, ophthalmology and cancer; directed differentiation of stem cells for tissue engineering applications, such as endothelial cells, cardiomyocytes, motor neurons and T-cells
 

Matthew Williams, Ph.D.

Focus on experiential education including engineering design, programming, data acquisition/processing, and fabrication. Research interests include control of prosthetics and assistive technology for stroke and spinal cord injury.
 

David Wilson, Ph.D.

Biomedical image processing; digital processing and quantitative image quality of X-ray fluoroscopy images; interventional MRI

 

 

Xin Yu, Sc.D.

Magnetic resonance imaging and spectroscopy; Metabolic imaging; Diabetes, obesity and metabolic syndrome; Stroke; Blood-brain barrier; Glymphatic function; Cerebrovascular physiology; Neuroimaging; Cardiac MRI

Maciej Zborowski, Ph.D.

Cleveland Clinic Lerner Research Institute

Cell separation; magnetic cell sorting; magnetic nanoparticles; immunomagnetic cell labeling; tissue magnetic susceptibility; red blood cell magnetic susceptibility; cell magnetophoresis; biomagnetism; intracellular iron; iron metabolism; circulating tumor cell separation; tissue progenitor cell separation; stem cell separation; particle tracking velocimetry; cell tracking velocimetry

Mei Zhang, Ph.D.

Nanotechnology for Cancer Diagnosis and Treatment; Imaging and Manipulation of Tumor Microenvironment; Cancer Immunotherapy; Adoptive T cell Immunotherapy