Timothy KInsella

Publications

Gurkan-Cavusoglu, E., Schupp, J., KInsella, T., & Loparo, K. A. (2013). Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells. IET systems biology, 7 (4), 114–124.
Gurkan Cavusoglu, E., Avadhani, S., Liu, L., KInsella, T., & Loparo, K. A. (2013). Developing an In Silico Model of the Modulation of Base Excision Repair using Methoxyamine for More Targeted Cancer Therapeutics. IET Systems Biology , 7 (2), 27-37.
Gurkan Cavusoglu, E., Schupp, J., KInsella, T., & Loparo, K. A. (2013). Quantitative Analysis of the Effects of Iododeoxyuridine and Ionizing Radiation Treatment on the Cell Cycle Dynamics of DNA Mismatch Repair Deficient Human Colorectal Cancer Cells. IET Systems Biology , 7 (4), 114-124.
Gurkan-Cavusoglu, E., Avadhani, S., Liu, L., KInsella, T., & Loparo, K. A. (2013). Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics. IET Systems Biology, 7 (2), 27–37.
KInsella, T., Gurkan-Cavusoglu, E., Du, W., & Loparo, K. A. (2011). Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers. Frontiers in oncology, 1
Zeng, X., Gurkan Cavusoglu, E., Loparo, K. A., & KInsella, T. A. (2009). Abstract# 460: The relationship between G2/M cell cycle arrest, and activation of autophagy and apoptosis following MMR processing of 6-thioguanine. Cancer Research, 69 (9 Supplement), 460–460.
Schupp, J., Gurkan Cavusoglu, E., Aziz, M., Seo, Y., Loparo, K. A., & KInsella, T. A. (2007). Computational modeling of the effect of the mismatch repair protein hMLH1 upon cell cycle responses and cytotoxicity of 5-iododeoxyuridine (IUdR) in colon cancer cells.. Cancer Research, 67 (9 Supplement), 4411–4411.
Gurkan-Cavusoglu, E., Schupp, J., Aziz, M., KInsella, T., & Loparo, K. A. (2007). Probabilistic modeling of DNA mismatch repair effects on cell cycle dynamics and iododeoxyuridine-DNA incorporation. Cancer research, 67 (22), 10993–11000.