Jane A. Little

Publications

Kucukal, E., Man, Y., Hill, A., Liu, S., Bode, A., Bakhshiani, M., Kadambi, J., Little, J., & Gurkan, U. (2020). Whole blood viscosity and red blood cell adhesion: Potential biomarkers for targeted and curative therapies in sickle cell disease. American Journal of Hematology, 95 (11), 1246-1256.
Man, Y., Kucukal, E., Bakhshiani, M., Bode, A., Little, J., & Gurkan, U. (2020). Standardized microfluidic assessment of red blood cell mediated microcapillary occlusion: association with clinical phenotype and hydroxyurea responsiveness in sickle cell disease. Microcirculation.
Kucukal, E., Man, Y., Quinn, E., Tewari, N., Bakhshiani, M., Ilich, A., Key, N., Little, J., & Gurkan, U. (2020). Red blood cell adhesion to ICAM-1 is mediated by fibrinogen and is associated with right-to-left shunts in sickle cell disease. Blood Advances, 4 (15), 3688-3698.
Noomuna, P., Risinger, M., Zhou, S., Seu, K., Man, Y., Bakhshiani, M., Sheik, D., Wan, J., Little, J., Gurkan, U., Turrini, F., Kalfa, T., & Low, P. (2020). Inhibition of Band 3 tyrosine phosphorylation: a new mechanism for treatment of sickle cell disease. British Journal of Haematology, 190 (4), 599-609.
Man, Y., Goreke, U., Kucukal, E., Hill, A., Bakhshiani, M., Liu, S., Bode, A., Solis-Fuentes, A., Nayak, L., Little, J., & Gurkan, U. (2020). Leukocyte adhesion to P-selectin and the inhibitory role of Crizanlizumab in sickle cell disease: A standardized microfluidic assessment. Blood Cells, Molecules, and Diseases, 83
Man, Y., Kucukal, E., Bakhshiani, M., Watson, Q., Bosch, J., Zimmerman, P., Little, J., & Gurkan, U. (2020). Microfluidic assessment of red blood cell mediated microvascular occlusion. Lab on a Chip, 20 (12), 2086-2099.
Hasan, M., Fraiwan, A., Bakhshiani, M., Alapan, Y., Ung, R., Akkus, A., Xu, J., Rezac, A., Kocmich, N., Creary, M., Oginni, T., Olanipekun, G., Hassan-Hanga, F., Jibir, B., Gambo, S., Verma, A., Bharti, P., Riolueang, S., Ngimhung, T., Suksangpleng, T., Thota, P., Werner, G., Shanmugam, R., Das, A., Viprakasit, V., Piccone, C., Little, J., Obaro, S., & Gurkan, U. (2020). Paper-based microchip electrophoresis for point-of-care hemoglobin testing. The Analyst, 145 (7), 2525-2542.
Yuan, C., Quinn, E., Kucukal, E., Kapoor, S., Gurkan, U., & Little, J. (2019). Priapism, hemoglobin desaturation, and red blood cell adhesion in men with sickle cell anemia. Blood Cells, Molecules, and Diseases, 79
Akkaya, B., Kucukal, E., Little, J., & Gurkan, U. (2019). Mercury leads to abnormal red blood cell adhesion to laminin mediated by membrane sulfatides. Biochimica et Biophysica Acta - Biomembranes, 1861 (6), 1162-1171.
Kucukal, E., Ilich, A., Key, N., Little, J., & Gurkan, U. (2018). Red Blood Cell Adhesion to Heme-Activated Endothelial Cells Reflects Clinical Phenotype in Sickle Cell Disease. American Journal of Hematology, 93 (8), 1050-1060.
Kucukal, E., Little, J., & Gurkan, U. (2018). Shear dependent red blood cell adhesion in microscale flow. Integrative Biology, 10 (4), 194-206.
Kim, M., Alapan, Y., Adhikari, A., Little, J., & Gurkan, U. (2017). Hypoxia enhanced adhesion of red blood cells in microscale flow. Microcirculation.
Alapan, Y., Kim, C., Adhikari, A., Gray, K., Gurkan-Cavusoglu, E., Little, J., & Gurkan, U. (2016). Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease. Translational Research [19315244], 173 , 74-91.e8.
Alapan, Y., Fraiwan, A., Kucukal, E., Hasan, M., Ung, R., Kim, M., Odame, I., Little, J., & Gurkan, U. (2016). Emerging Point-of-Care Technologies for Sickle Cell Disease Screening and Monitoring. Expert Review of Medical Devices [17434440], 13 (12), 1073-1093.