| Title | Novel, non-invasive imaging approach to identify patients with advanced non-small cell lung cancer at risk of hyperprogressive disease with immune checkpoint blockade. |
| Publication Type | Journal Article |
| Year of Publication | 2020 |
| Authors | Vaidya, P, Bera K, Patil PD, Gupta A, Jain P, Alilou M, Khorrami MH, Velcheti V, Madabhushi A |
| Journal | Journal for immunotherapy of cancer |
| Volume | 8 |
| Issue | 2 |
| Date Published | 2020 Oct |
| ISSN | 2051-1426 |
| Abstract | Hyperprogression is an atypical response pattern to immune checkpoint inhibition that has been described within non-small cell lung cancer (NSCLC). The paradoxical acceleration of tumor growth after immunotherapy has been associated with significantly shortened survival, and currently, there are no clinically validated biomarkers to identify patients at risk of hyperprogression. |
| DOI | 10.1136/jitc-2020-001343 |
| PDF Link | |
| Alternate Journal | J Immunother Cancer |
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