| Title | Disorder in Pixel-Level Edge Directions on T1WI Is Associated with the Degree of Radiation Necrosis in Primary and Metastatic Brain Tumors: Preliminary Findings. |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Prasanna, P, Rogers L, Lam TC, Cohen M, Siddalingappa A, Wolansky L, Pinho M, Gupta A, Hatanpaa KJ, Madabhushi A, Tiwari P |
| Journal | AJNR. American journal of neuroradiology |
| Volume | 40 |
| Issue | 3 |
| Pagination | 412-417 |
| Date Published | 2019 Mar |
| ISSN | 1936-959X |
| Abstract | Co-occurrence of local anisotropic gradient orientations (COLLAGE) is a recently developed radiomic (computer extracted) feature that captures entropy (measures the degree of disorder) in pixel-level edge directions and was previously shown to distinguish predominant cerebral radiation necrosis from recurrent tumor on gadolinium-contrast T1WI. In this work, we sought to investigate whether COLLAGE measurements from posttreatment gadolinium-contrast T1WI could distinguish varying extents of cerebral radiation necrosis and recurrent tumor classes in a lesion across primary and metastatic brain tumors. |
| DOI | 10.3174/ajnr.A5958 |
| PDF Link | |
| Alternate Journal | AJNR Am J Neuroradiol |
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