Association of Peritumoral Radiomics With Tumor Biology and Pathologic Response to Preoperative Targeted Therapy for HER2 (ERBB2)-Positive Breast Cancer.

TitleAssociation of Peritumoral Radiomics With Tumor Biology and Pathologic Response to Preoperative Targeted Therapy for HER2 (ERBB2)-Positive Breast Cancer.
Publication TypeJournal Article
Year of Publication2019
AuthorsBraman, N, Prasanna P, Whitney J, Singh S, Beig N, Etesami M, Bates DDB, Gallagher K, Bloch NB, Vulchi M, Turk P, Bera K, Abraham J, Sikov WM, Somlo G, Harris LN, Gilmore H, Plecha D, Varadan V, Madabhushi A
JournalJAMA network open
Volume2
Issue4
Paginatione192561
Date Published2019 Apr 05
ISSN2574-3805
Abstract

There has been significant recent interest in understanding the utility of quantitative imaging to delineate breast cancer intrinsic biological factors and therapeutic response. No clinically accepted biomarkers are as yet available for estimation of response to human epidermal growth factor receptor 2 (currently known as ERBB2, but referred to as HER2 in this study)-targeted therapy in breast cancer.

DOI10.1001/jamanetworkopen.2019.2561
PDF Link

http://www.ncbi.nlm.nih.gov/pubmed/31002322?dopt=Abstract

Alternate JournalJAMA Netw Open

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