Anant Madabhushi, PhD and his collaborator Soumya Ghose, PhD were awarded the patent, “Predicting biochemical recurrence in pre-treatment prostate magnetic resonance imaging (MRI) with field effect induced organ distension (FORGE)”.
USSN: 10,607,112; March 31, 2020
Inventors: Anant Madabhushi, Soumya Ghose
Abstract: Embodiments predict prostate cancer (PCa) biochemical recurrence (BCR) employing an image acquisition circuit that accesses a pre-treatment image of a region of tissue demonstrating PCa; a segmentation circuit that segments a prostate capsule represented in the image; a registration circuit that registers the segmented prostate with a BCR- median template, and generates a registered surface of interest (SOI) mask by registering an SOI mask with the registered prostate; a mask circuit that generates a patient-specific SOI mask from the registered prostate and the registered SOI mask, and generates a patient-specific SOI mesh from the patient-specific SOI mask; a field effect induced organ distension (FOrge) circuit extracts a set of FOrge features from the patient-specific SOI mesh, and computes a probability that the region of tissue will experience BCR; and a classification circuit classifies the region of tissue as likely to experience BCR based on the probability.
