Center for Computational Imaging and Personalized Diagnostics researchers awarded a patent on February 16, 2021

Thursday, February 25, 2021 - 00:13

On February 16th, a patent was awarded to inventors from the Center for Computational Imaging and Personalized Diagnostics (CCIPD): “Probabilistic atlases of post-treatment multi-parametric MRI scans reveal distinct hemispheric distribution of glioblastoma progression versus pseudo-progression”. Congratulations to Pallavi Tiwari, PhD, assistant professor, biomedical engineering, CCIPD lead faculty, and leader of the BRIC Lab; Marwa Ismail, research associate with CCIPD and BRIC Lab; and Anant Madabhushi, PhD, Donnell Institute Professor, biomedical engineering, and director of CCIPD. Read details about the patent below.

“Probabilistic atlases of post-treatment multi-parametric MRI scans reveal distinct hemispheric distribution of glioblastoma progression versus pseudo-progression”

United States Serial Number (USSN): 10,921,408, February 16, 2021.

Inventors: Tiwari; Pallavi, Ismail; Marwa, Madabhushi; Anant
 
Abstract: Embodiments discussed herein facilitate generating a quantitative population atlas of tumor progression (TP) versus pseudo-progression (PsP) in Glioblastoma (GBM). A first set of embodiments discussed herein relates to generating a quantitative population atlas of TP versus PsP based on a plurality of multi-parametric (mpMRI) studies of a population of patients demonstrating GBM. A second set of embodiments discussed herein relates to computing a probability that a patient will experience PsP or TP based on a DICE analysis of a mapping of a diagnostic mpMRI study associated with the patient into the quantitative population atlas space.