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Neural Engineering & Rehabilitation


Stimulating the Future of Medicine

Neural engineering and rehabilitation research applies neuroscience and engineering methods to analyze central and peripheral nervous system function and to design clinical solutions for neurological disorders or injury. Through the application of basic science and engineering techniques, neural engineers develop methods to record from and exert control over the nervous system and associated organ systems. Primary faculty, associated faculty, research associates, and students work in three national centers of education and research in neural engineering and rehabilitation. Our research teams collaborate with four local major medical facilities: MetroHealth Medical Center, University Hospitals Case Medical Center, Cleveland Clinic, and The Louis Stokes Cleveland VA Medical Center. Neural engineering facilities allow researchers to take ideas from basic science through experimental testing and to clinical deployment. Neural engineering research teams are funded by commercial partnerships and grants, including those from the State of Ohio, National Institutes of Health, and other federal sources. Below are a few examples of the ongoing research and applications in neural engineering and rehabilitation.

Neuromodulation
Clinical and experimental technologies for treating and managing consequences of stroke, epilepsy, pain, spinal cord injury, genitourinary function, movement disorders, autonomic functions, and psychiatric disorders.

Prosthetics and Orthotics
Implanted devices to directly communicate with residual nervous system functions for the control of assistive technologies, as well as to provide sensory feedback in amputee prosthetics.

Neural Interfaces
Design of both stimulating and recording electrode technologies for interfacing with the nervous system.

Neural and Biomechanical Computation
Simulation tools for evaluating Neuromodulation, Prosthetic, and Neural Interface technologies.

 

 

Faculty

A. Bolu Ajiboye, Ph.D.

Development and control of brain-computer-interface (BCI) technologies for restoring function to individuals who have experienced severely debilitating injuries to the nervous system, such as spinal cord injury and stroke

 

Jeffrey R. Capadona, Ph.D.

To develop an understanding for how the neuroinflammatory response facilitates acute and long-term neural device performance.

 

Patrick Crago, Ph.D.

Control of neuroprostheses for restoration of motor function; neuromechanics; and modeling of neuromusculoskeletal systems


 

Dominique M. Durand, Ph.D.

Neural engineering; neural interfacing; neural prostheses; computational neuroscience; neural dynamics; neuromodulation; neurophysiology and control of epilepsy

 

Kenneth J. Gustafson, Ph.D.

Neural engineering; neural prostheses; neurophysiology and neural control of genitourinary function; devices to restore genitourinary function; and functional neuromuscular stimulation

 

Robert Kirsch, Ph.D.

Restoration of movement using neuroprostheses; neuroprosthesis control system design; natural control of human movements; biomechanics of movement; computer-based modeling; and system identification

 

Cameron McIntyre, Ph.D.

Chronic high-frequency electrical stimulation of subcortical brain structures-- or deep brain stimulation (DBS)-- and its applications as a therapy for neurological disorders.

 

P. Hunter Peckham, Ph.D.

Rehabilitation engineering in spinal cord injury; neural prostheses; and functional electrical stimulation and technology transfer

 

Ronald Triolo, Ph.D.

Restore/ or enhance the upright and seated mobility, posture and balance in individuals with neuro-musculo-skeletal disorders.

 

Dustin Tyler, Ph.D.

Neuromimetic neuroprostheses; laryngeal neuroprostheses; clinical implementation of nerve electrodes; cortical neuroprostheses; minimally invasive implantation techniques; and modeling of neural stimulation and neuroprostheses
 

 

Research Faculty

Musa Audu, Ph.D.

Human musculoskeletal modeling and development of control systems for rehabilitation of individuals with spinal cord injury and other balance disorders. Design of rehabilitation devices for physically challenged individuals.

 

Niloy Bhadra, M.D., Ph.D.

Experimental and computational studies of high frequency waveforms for reversible conduction block of peripheral nerves; design, testing and implementation of neuroprosthetic systems for the upper limb

 

Tina Vrabec, Ph.D.

Direct current block of the peripheral nerve; New electrode technology was developed to provide direct current nerve block safely, allowing several novel nerve block waveforms to be tested that have the potential to address a wide variety of clinical issues over a varied group of patients.
 

 

Associated Faculty

Alberts, Jay
Assistant Professor

Cleveland Clinic Lerner College of Medicine
Molecular Medicine

phone: (216) 445-322
fax: (216) 444-9198
email: jay.alberts@case.edu

Burgess, Richard C.
Adjunct Professor

Cleveland Clinic Foundation
Department of Neurology

phone: (216) 444-7008
fax: (216) 445-4378
email: burgesr@ccf.org

Chae, John
Professor

MetroHealth Medical Center
Physical Medicine & Rehabilitation

phone: (216) 778-3472
fax: (216) 778-5560
email: jchae@metrohealth.org

Chiel, Hillel J.
Professor

Case Western Reserve University
Biology

phone: (216) 368-3846
fax: (216) 368-4672
email: hillel.chiel@case.edu

Jenkins, Michael
Assistant Professor

University Hospitals
Pediatrics

email: michael.jenkins@case.edu

Kilgore, Kevin
Adjunct Assistant Professor

MetroHealth Medical Center
Orthopaedics

phone: (216) 778-3801
fax: (216) 778-8409
email: kevin.kilgore@case.edu

Taylor, Dawn
Assistant Professor

Cleveland Clinic Lerner College of Medicine
Lerner Research Institute

phone: (216) 778-3480
fax: (216) 778-4259
email: dawn.taylor@case.edu, taylord8@ccf.org