Online Master's in Biomedical Engineering @ Case.edu
Biomedical Engineering Alliance
Shedding Light on the Nervous System
Alumni Couple Commit Gift to Computer Imaging Lab
Capitalizing on Opportunities in Medical Imaging

Research

Laboratory of Biomedical Sensing

Research in this laboratory encompasses cost-effective body-fluid diagnostics, single cell level cancer research, and the development of micro-miniature implantable sensors for glucose and electrolytes for use by diabetic patients. Diagnostics in 1-20 microliter body fluids and other samples is performed using micro fabricated electrochemical and optical sensors and an electrochemical micro-pH-stat. We also developed an equivalent of rotating electrode for microliter samples, called the rotating sample system. For cellular research, a diffusional microburet has been developed to continuously deliver reagents and drugs into single live cells. Fluorescence microscopy is employed to quantitate intracellular accumulation. Efflux is measured with a carbon fiber based electrochemical microsensor that can detect Adriamycin, a cancer drug, extruded from cells at very low concentrations. Neurochemical studies as well as measurements at epithelial cell layers are also performed with different microscopic sensing schemes.