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Gratzl Publications

About 50 publications appeared from my lab during my tenure at CWRU, out of a total of about 100. The average number of citations per article since 1996 (the year of tenure) up to 2006 is 24. This includes all the papers published in that period. The h index is 21 and i10 index=35 (Google Scholar). Early publications appeared mainly in the Hungarian Journal of Chemistry which is no longer indexed. Recent publications after 2006 are not included since a citation base requires several years to build up. All the papers published while at CWRU appeared in the best international journals of the respective areas: Physical Chemistry, Neuroscience, Biophysical Journal, Analytical Chemistry, European Journal of Biophysics, Journal of Chemical Physics and Physical Chemistry, Sensors and Actuators, and others. An example is Analytical Chemistry where I have published more than 30 research articles thus far. Analytical Chemistry is the best in the World in the broad fields of chemical and biomedical sensing and measurements.

Below publications and presentations from 1990, the year of the beginning of my CWRU employment, are included only.

CODES: underline denotes corresponding author or presenter; Italics denote supervised students and fellows

 

Publications:

  1. Gratzl M, Hsu D, Riley A, Janata J: Electrochemically deposited polythiophene. 1. Ohmic drop compensation and the polythiophene paradox. Journal of Physical Chemistry 94, 15, 5973-5981 (1990)
  2. Hsu D, Gratzl M, Riley A, Janata J: Electrochemically deposited polythiophene. 2. Dry and wet relaxation. Journal of Physical Chemistry 94, 15, 5982-5989 (1990)
  3. Gratzl M, Tarcali J, Juhász G, Pungor E: Local depletion of monoamines induced with in vivo voltammetry in the cat brain. Neuroscience, 41, 287-293 (1991)
  4. Yi C, Gratzl M : Diffusional microtitration: acid/base titrations in pico- and femtoliter samples. Anal. Chem. 65, 2085-2088 (1993)
  5. Yi C, Gratzl M: Diffusional microtitration: reagent transport from a diffusional microburet into microscopic samples. Anal. Chem. 66, 1976-1982 (1994)
  6. Hui K, Gratzl M: Anomalies of convolutional smoothing and differentiation. Anal. Chem. 68, 1054-1057 (1996)
  7. Yi C, Huang DJ, Gratzl M: Microscopic diffusional titration: complexometric determination of metal ions. Anal. Chem. 68, 1580-1584 (1996)
  8. Xie H, Gratzl M : Diffusional microtitration of metal ions in 1-20 microliter samples. Anal. Chem. 68, 3665-3669 (1996)
  9. Diefes R, Hui K, Dudik L, Liu CC, Gratzl M: Sample/reagent adosorption on alumina vs Pyrex substrates of microfabricated electrochemical sensors. Sensors and Actuators B Chem, 2133-136 (1996)
  10. Hui K, Gratzl M: Diffusonal microtitration of 20 microliter samples with optical indication. Anal. Chem. 69, 695-698 (1997)
  11. Cserey A, Gratzl M: Rotating sample system: an equivalent of the rotating electrode for microliter samples. Anal. Chem. 69, 3687-3692 (1997)
  12. Kashyap R, Gratzl M: Electrochemistry in microscopic domains. The electrochemical cell and its voltammetric and amperometric response. Anal. Chem. 70, 1468-1476 (1998)
  13. Kumar GK, Overholt JL, Bright GR, Hui KY, Lu H, Gratzl M, Prabhakar NR: Release of dopamine and norepinephrine by hypoxia from PC12 cells. Am. J. Phys.: Cell Phys. 274, C1592-1600 (1998)
  14. Yi C, Gratzl M:  Continuous in situ electrochemical monitoring of doxorubicin efflux from sensitive and drug resistant cancer cells. Biophys. J. 75, 2255-2261 (1998)
  15. Yi C, Saidel G, Gratzl M: Single cell model for simultaneous drug delivery and efflux. Annals of Biomed. Eng. 27, 208-218 (1999)
  16. Gratzl M, Yi C, Lu H, Matsumoto T, Bright G.R: Fine chemical manipulation of microscopic liquid samples. Part 1. Droplet loading with chemicals. Anal. Chem. 71, 2751-2756 (1999)
  17. Lu H, Matsumoto T, Gratzl M: Fine chemical manipulation of microscopic liquid samples. Part 2. Consuming and non-consuming schemes. Anal. Chem. 71, 4896-4902 (1999)
  18. Kashyap R, Gratzl M: Adjusting the distance of electrochemical microsensors from secreting cell monolayers on the micrometer scale using impedance. Anal. Chem. 71, 2814-2820 (1999)
  19. Lu H, Gratzl M: Monitoring drug efflux from sensitive and drug resistant single cancer cells with microvoltammetry. Anal. Chem. 71, 2821-2830 (1999)
  20. Lu H, Gratzl M: Optical detection in microscopic domains. Part 1. Monitoring chemical manipulations with absorption spectrometry. Anal. Chem. 72, 1569-1576 (2000)
  21. Tohda K, Lu H, Umezawa Y, Gratzl M: Optical detection in microscopic domains. Part 2. Inner filter effects for monitoring non-fluorescent molecules with fluorescence. Anal. Chem. 73, 2070-2077 (2001)
  22. Cserey A, Gratzl M: Stationary-state oxidized platinum microsensor for selective and on-line monitoring of nitric oxide in biological preparations. Anal. Chem. 73(16), 3965-3974 (2001)
  23. Yoshida M, Tohda K, Gratzl M: Hydrodynamic micromanipulation of individual cells onto patterned attachment sites on bioelectromechanical system chips. Anal.Chem. 75(17), 4686-4690 (2003)
  24. Yoshida M, Tohda K, Gratzl M: Optical detection in microscopic domains. Part 3. Confocal analysis of fluorescent amphiphilic molecules. Anal. Chem., 75(22), 6133-6140 (2003)
  25. Tohda K, Gratzl M: Microscopic, continuous, optical monitor for interstitial electrolytes and glucose. J. Chem. Phys. Chem. 4, 155-160 (2003) Invited article, featured also on the journal’s cover
  26. Nair S, Gratzl M: Assessing transport at live cell preparations: a case study on anomalies of deconvolution via discrete Fourier transform. Trends in Anal. Chem. 23(6), 459-467 (2004) Invited article
  27. Shetty G, Gratzl M: Rotating sample system: a simple equivalent of a rotating disk electrode for detection of trace Lead in microliter samples. Chem. Sensors 6, 252-254 (2004)
  28. Nair S, Gratzl M: Deconvolution of concentration recordings at live cell preparations via shape error optimization. Anal. Chem., 77(9), 2875-2881 (2005)
  29. Shetty G, Syed N, Tohda K, Gratzl M: Hydrodynamic electrochemistry in 20 μL drops in the rotating sample system. Anal. Sci. 21(10), 1155-1160 (2005) Article featured on the cover of the journal and designated as “hot article”
  30. Tohda K, Gratzl M: Micro-miniature autonomous optical sensor array for monitoring ions and metabolites 1: design, fabrication, and data analysis. Anal. Sci. 22(3), 383-388 (2006)
  31. Tohda K, Gratzl M: Micro-miniature autonomous optical sensor array for monitoring ions and metabolites 2: color response to pH, K+, and glucose. Anal. Sci. 22(7): 937-941 (2006)
  32. Kao L, Hsu H, Shetty G, Gratzl M: Electrochemical pH stat for microliter fluid specimens. ECS Transactions, 3(10), 117-124 (2006)
  33. Oruganti P, Gratzl M: Rate-limiting hydrodynamic resistance for controlled reagent delivery for laboratory solution preparation. Anal. Chem. 79(6): 2541-2545 (2007)
  34. Gratzl M: Micro-electrochemistry for biomedical applications. In: Recent advances in analytical electrochemistry. ISBN: 978-81-7895-274-1, 251-277 (2007)
  35. Nair S, Kashyap R, Laboisse CL, Hopfer U, Gratzl M: Time resolved secretion of chloride from a monolayer of mucin secreting epithelial cells. Eur. Biophys. J. 37(4): 411-419 (2008)
  36. Sheth D, Suresh G, Yang J, Ladas T, Zorman CA, Gratzl M: MEMS device to monitor biological oxygen uptake at arrays of single cells and small cell clusters. Electroanalysis 20(6): 627-634 (2008)
  37. Kao LT, Hsu H, Gratzl M: Reagentless pH-stat for microliter fluid specimens. Anal. Chem. 80, 4065-4069 (2008)
  38. Yoshida M, Tohda K, Gratzl M: Controlled diffusion for laboratory solution preparation. Anal. Bioanal. Chem. 392(3): 471-477 (2008)
  39. Nair S, Gratzl M: Effect of sampling rate in the evaluation of cellular transport. Anal Chem. 80(20): 7684-9 (2008)
  40. Kao LT, Shetty GN, Gratzl M: Determination of critical micelle concentration with the rotating sample system, Anal. Bioanal. Chem. 392(7-8): 1391-6 (2008)
  41. Gratzl M, Yi C, Bright RG: Continuous and quantitative delivery of molecules into individual cells with a diffusional microburet. Anal. Chem. 80(23): 9310-9315 (2008)
  42. Sheth D, Gratzl M: Spatially averaging electrodes. Anal. Chem. 81 (6): 2129–2134 (2009)
  43. Kao LT, Gratzl M: Serum cholinesterase assay using a reagent-free micro pH-stat. Anal. Biochem. 389: 93–96 (2009)
  44. Oruganti P, Gratzl M: Temporal ratiometry to assess dynamic concentration distributions of fluorescent molecules in single live cells during continuous diffusional dosing. Anal. Bioanal. Chem. 395 (2): 449-456 (2009)
  45. Tohda K, Yamamoto T, Gratzl M: Modeling the response function of enzyme-based optical glucose-sensing capsules. J. Supramol. Chem. 22(7): 425-433 (2010)
  46. Nair S, Kashyap R, Laboisse CL, Hopfer U, Gratzl M: Time-resolved release of calcium from an epithelial cell monolayer during mucin secretion. Eur. Biophys. J. 40(2): 165-175 (2011)
  47. Pähler M, Schumann W, Gratzl M: Simultaneous visualization of surface topography and concentration field with scanning electrochemical microscopy using a single electrochemical probe and impedance spectroscopy. J. Chem. Phys. Chem. 12, 2798-2805 (2011)
  48. Lee K L, Hubbard LC, Hern S, Yildiz I, Gratzl M, Steinmetz N F: Shape matters: the diffusion rates of TMV rods and CPMV icosahedrons in a spheroid model of extracellular matrix are distinct. Biomater. Sci. 1, 581-588 (2013)
  49. Sheth D, Gratzl M: Differential linear scan voltammetry: analytical performance in comparison with pulsed voltammetry techniques. Anal. Bioanal. Chem. 405, 16, 5539-5547 (2013) PMID 23624955
  50. Potdar AA, Sarkar J, Das NK, Gosh P, Gratzl M, Fox PL, Saidel GM: Computational modeling and analysis of iron release from macrophages. PLOS Computations Biology 12: 243-267 (2014)
  51. Ahuja P, Peshkova MA, Hemphill B, Gratzl M: Minimizing color interference from biomedical samples in optode-based measurements. Sensors and Actuators II Chemical (12): 212-216 (2014)
  52. Ahuja P, Nair S, Narayan S, Gratzl M: Functional imaging of chemically active surfaces with optical reporter microbeads. 10(9), PPLOS ONE (2015)
  53. Peshkova M, Ahuja P, Tohda K, Gratzl M: Optochemical sensor array for metabolic monitoring. Anal. Bioanal. Chem., pending

 

Conference Proceedings, Abstracts, and Invited Presentations from 1990:

Out of 213 presentations 107 were invited (seminars and keynote and plenary talks)

  • Gratzl M: Potentiometric sensor for buffer capacity. Am. Chem. Soc. Meeting, Atlanta, Georgia, May 1991. Oral presentation
  • Gratzl M: Diffusional microtitration. Gordon Research Conference on Analytical Chemistry, Holderness, New Hampshire, August 1991. Invited short talk
  • Gratzl M: Spatially averaging electrochemical sensors. Gordon Research Conference on Electrochemistry, Ventura, California, January 1992. Invited short talk
  • Gratzl M: Spatially averaging electrochemical sensors. SAC’92 International Conference on Analysis and Spectrometry, Reading, United Kingdom, September 1992. Invited talk
  • Tsao W, Gratzl M: Study of monoamine depletion in mammalian brain with voltammetric carbon fiber microelectrode. Biomedical Engineering Society Fall Meeting, Salt Lake City, Utah, October 1992. Oral presentation
  • Yi C, Gratzl M: A new device for intracellular reagent/drug delivery. . Biomedical Engineering Society Fall Meeting, Salt Lake City, Utah, October 1992. Oral presentation
  • Diefes R, Gratzl M: Diffusional titration of biomedical ultramicrosamples. Biomedical Engineering Society Fall Meeting, Salt Lake City, Utah, October 1992. Oral presentation
  • Prabhakar N, Agani F, Hui K, Gratzl M: Detection of neurochemical release by chemical stimulants and hypoxia from PC-12 and carotid body cells with microvoltammetry. FASEB Meeting, New Orleans, Louisiana, March 1993. Invited talk
  • Gratzl M: Simultaneous influx/efflux studies on single cells. Gordon Research Conference on Bioanalytical Sensors, Ventura, California, March 1993. Invited short talk
  • Gratzl M: Electrochemical microsensors for in vitro and in vivo studies. Research Day of the Case Center for Electrochemical Science, Case Western Reserve University, Cleveland, Ohio, March 1993. Invited talk
  • Yi C, Gratzl M: Trace analysis of the anticancer drug Adriamycin using carbon fiber microvoltammetry for single cell drug resistance studies. International Electroanalytical Symposium, Indianapolis, Indiana, May 1993. Invited keynote lecture
  • Diefes R, Hui K, Gratzl M: Diffusional microtitration system for the analysis of biomedical samples. International Electroanalytical Symposium, Indianapolis, Indiana, May 1993. Oral presentation
  • Yi C, Bright G, Gratzl M: New approach to assess simultaneous influx/efflux of the anticancer drug Adriamycin at human cancer cells. 15th Annual International Conference of the IEEEI-EMBS, San Diego, California, October 1993. Plenary lecture
  • Gratzl M: New microchemical techniques for cellular studies. Laboratory of Neurophysiology, Czech Academy of Sciences, Prague, Czech Republic, January 1994. Invited seminar
  • Yi C, Gratzl M: Continuous monitoring of Adriamycin efflux from sensitive and drug resistant cancer cells using a carbon fiber microelectrode. Case Western Reserve University, Frontiers in Chemistry Symposium, Cleveland, Ohio, September 1994. Invited talk
  • Gratzl M: Cost-effective diagnosis of microliter volumes of body fluids. Biomedical Engineering Society Fall Meeting, Tempe, Arizona, October 1994. Invited talk
  • Yi C, Vinogradova O, Gratzl M: Drug resistance studies on cell populations using microvoltammetry for efflux detection. Biomedical Engineering Society Fall Meeting, Tempe, Arizona, October 1994. Invited talk
  • Hui K, Diefes R, Dudik L, Liu CC, Gratzl M: Determination of cysteine in 20 microliter body fluid samples. Biomedical Engineering Society Fall Meeting, Tempe, Arizona, October 1994. Oral presentation
  • Gratzl M, Hui K, Xie H: A simple approach to analyze ions, molecules and enzymes in microvolumes of body fluids. Biomedical Engineering Society Fall Meeting, Tempe, Arizona, October 1994. Invited talk
  • Yi C, Gratzl M: Continuous efflux measurement of the anticancer drug Adryamicin from cancer cells using a carbon fiber microelectrode. Biomedical Engineering Society Fall Meeting, Tempe, Arizona, October 1994. Invited talk
  • Yi C, Saidel G, Gratzl M: Continuous delivery of ions and drugs into single cells by a diffusional microburet. IEEE-EMBS Meeting, Baltimore, Maryland, November 1994. Oral presentation
  • Hui K, Diefes R, Dudik L, Liu CC, Gratzl M: Analysis of ultramicro biomedical samples with microfabricated chemical sensors: sample/reagent adsorption on alumina vs Pyrex substrates. IEEE-EMBS Meeting, Baltimore, Maryland, November 1994. Oral presentation
  • Gratzl M: A cost-effective clinical diagnostic technology and related applications in single cell studies. University Hospitals Critical Care Division in Rainbow Babies’ and Children’s Hospital, Cleveland, Ohio, January 1995. Invited seminar
  • Gratzl M: New microtechniques in biomedical sensing. Department of Bioengineering, University of Utah, Salt Lake City, Utah, January 1995. Invited seminar
  • Xie H, Gratzl M: Simple and cost-effective determination of some trace metals in microsamples of body fluids. IEEE-EMBS Summer Conference, Beaver Creek, Colorado, June 1995. Oral presentation
  • Fang X, Yi C, Bright G, Gratzl M: Continuous drug delivery into single cancer cells bypassing spontaneous uptake mechanisms. IEEE-EMBS Summer Conference, Beaver Creek, Colorado, June 1995. Oral presentation
  • Gratzl M: New tools for cellular studies. Bayer Science Forum, Bayer Corporation, Elkhart, Indiana, August 1995. Invited seminar
  • Gratzl M: Development of new microtools for fine chemical manipulation of microscopic droplets and for single cell studies. Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, October 1995. Invited seminar
  • Gratzl M: Novel technologies for cost-effective body fluid diagnostics and for single cell studies. Department of Physiology and Biophysics, Cleveland State University, Cleveland, Ohio, February 1996. Invited seminar
  • Gratzl M: Electrochemistry in microvolumes of sample and biomedical applications. Electrochemical Society Meeting, Cleveland, September 1996. Invited talk
  • Traore M, Kashyap R, Hopfer U, Bertrand C, Gratzl M: Ion-selective micrielectrodes for monitoring electrolyte and mucus secretion from monolayers of epithelial cells. Biomedical Engineering Society Fall Meeting, Boston, Massachusetts, October 1995. Oral presentation
  • Gratzl M: Electrochemical and optical techniques in microvolumes of sample and biomedical applications. Bayer Science Forum, Bayer Corporation, Elkhart, Indiana, October 1996. Invited seminar
  • Gratzl M, Wang HW, Yi C: A voltammetric microsensor for drug resistance studies in small cancer cell populations and for medical applications. Electrochemical Society Meeting, San Antonio, Texas, October 1996. Oral presentation
  • Cserey A, Gratzl M: A simple equivalent of a rotating electrode system for microliter samples. Electrochemical Society Meeting, San Antonio, Texas, October 1996. Oral presentation
  • Gratzl M, Kashyap R: Adjusting the distance of electrochemical microsensors from cell monolayers on the micrometer scale using impedance. Electrochemical Society Meeting, Montreal, Canada, May 1997. Oral presentation
  • Gratzl M: Electrochemistry in restricted biological spaces. Bayer Science Forum, Bayer Corporation, Elkhart, Indiana, August 1997. Invited seminar
  • Gratzl M: Novel ways of chemical diagnostics in microliter samples. Edison Biotechnology Center, Cleveland, Ohio, August 1997. Invited seminar
  • Gratzl M: Sensing schemes for biomedical applications in microsamples and single live cells. Universidad de Alcala, Madrid, Alcala de Henares, Spain, October 1997. Invited seminar
  • Cserey A, Gratzl M: A simple equivalent of a rotating electrode system for microliter samples. Biomedical Engineering Society Fall Meeting, San Diego, California, October 1997. Oral presentation
  • Kashyap R, Gratzl M: Adjusting the distance of electrochemical microsensors from secreting cell monolayers on the micrometer scale using impedance.  Biomedical Engineering Society Fall Meeting, San Diego, California, October 1997. Oral presentation
  • Kashyap R, Gratzl M: Electrochemistry in microscopic domains: a model system to interpret voltammetry measurements in restricted biological spaces. IEEE-EMBS Annual Meeting, Chicago, Illinois, October/November 1997. Oral presentation
  • Gratzl M: Physicochemical microtechniques for single cell studies. Department of Chemical Engineering, Universitat Rovira i Virgili, Tarragona, Spain, November 1997. Invited seminar
  • Gratzl M: Electrochemistry in microscopic domains. Bayer Science Forum, Bayer Corporation, Elkhart, Indiana, December 1997. Invited seminar
  • Gratzl M: A new platform technology for chemical diagnostics in microlitert samples. Keithley Instruments, Solon, Ohio, March 1998. Invited seminar
  • Gratzl M: Drug resistance studies on single cancer cells. Central Research Laboratories, London, UK, March 1998. Invited seminar
  • Gratzl M: Electrocatalytic effects at microelectrodes in restricted spaces. Abo Akademi, May 1998. Invited seminar
  • Lu H, Gratzl M: Monitoring drug efflux from sensitive and multidrug resistant single cancer cells with microvoltammetry. 193rd Meeting of the Electrochemical Society, San Diego, California, May 1998. Oral presentation
  • Kashyap R, Gratzl M: Electrochemistry in microscopic domains. 193rd Meeting of the Electrochemical Society, San Diego, California, May 1998. Oral presentation
  • Gratzl M: Using natural forces and phenomena for novel analytical schemes in microsamples and on the single cell level. Department of Biotechnology, University of Lund, Lund, Sweden, June 1998. Invited Seminar
  • Gratzl M: New schemes for single cell studies. Department of Physical Chemistry, Saint-Petersburg State University, Saint Petersburg, Russia, June 1998. Invited seminar
  • Gratzl M: Using natural forces and phenomena for body fluid diagnostics. Cost-Effective Health Care Technologies Conference, NSF - Whitaker Foundation, Washington, D.C., July 1998. Invited talk
  • Gratzl M: New techniques for microscopic physicochemical and cellular studies. Central Research Laboratories, London, United Kingdom, July 1998. Invited seminar
  • Gratzl M: Cost-effective diagnostics in microliter samples of body fluids. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Cserey A, Gratzl M: Microfabricated rotating sample system for diagnostics in single drops of body fluids. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Lu H, Gratzl M: Optical detection of drug transport into microdroplets and single cancer cells. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Lu H, Gratzl M: Monitoring drug efflux form sensitive and multidrug resistant single cancer cells with microvoltammetry. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Kashyap R, Laboisse CL, Hopfer U, Gratzl M: Monitoring ionic secretions from epithelial cells with ion selective microelelectrodes. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Cserey A, Gratzl M: Novel microsensor for in situ monitoring of NO. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Kashyap R, Beigi R, Gratzl M: Micro-electrochemical measurements in restricted biological spaces. Biomedical Engineering Society Fall Meeting, Cleveland, Ohio, October 1998. Invited talk
  • Gratzl M: Monitoring drug efflux from sensitive and multidrug resistant single cancer cells with microvoltammetry. Biomedical Engineering Society Fall meeting, Cleveland, Ohio, October 1998. Invited talk
  • Gratzl M: Micro-electrochemical measurements in restricted biological spaces. Biomedical Engineering Society Fall meeting, Cleveland, Ohio, October 1998. Invited talk
  • Gratzl M: Optical detection of drug transport into micro-droplets and single cancer cells. Biomedical Engineering Society Fall meeting, Cleveland, Ohio, October 1998. Oral presentation
  • Gratzl M: Electrochemical and optical techniques in microscopic domains and their applications for cancer research at the single cell level. Penn State, Dept. of Chemistry, State College, Pennsylvania, September 1999. Invited seminar
  • Gratzl M: Biochemical diagnostics in liquid ultramicrosamples and at single live cells. HRL Laboratories, Malibu, California, October 1999. Invited seminar
  • Gratzl M: Electrochemical and optical techniques in microscopic domains and their applications for neuroscience research at the organ, tissue and single cell levels. Neuroscience Dept., Case Western Reserve University, Cleveland, Ohio, November 1999. Invited seminar
  • Gratzl M: Electrochemical and optical detection in microscopic domains and biomedical applications. Dept. of General and Analytical Chemistry, Techn. Univ. of Budapest, Hungary, February 2000. Invited seminar
  • Gratzl M: Biochemical diagnostics in microliter samples and at the single cell level. BIOMEC, Inc., Cleveland, Ohio, March 2000. Invited talk
  • Gratzl M: Monitoring drug efflux from drug sensitive and multidrug resistant single cancer cells with microvoltammetry. CMACS conference (ACS), Cincinnati, Ohio, May 2000, Invited talk
  • Tohda K, Gratzl M: Theory and practice of the rotating sample system for trace analyses. CMACS conference (ACS), Cincinnati, Ohio, May 2000. Invited talk
  • Huang X, Gratzl M: Determination of 1-20 µL samples using diffusional microtitration with various indication schemes. CMACS conference (ACS), Cincinnati, Ohio, May 2000. Poster presentation
  • Yoshida M, Lu H, Gratzl M: Monitoring doxorubicin delivery into microscopic aqueous samples with confocal microscopy. CMACS conference (ACS), Cincinnati, Ohio, May 2000, May 2000. Oral presentation
  • Oruganti P, Gratzl M: Catalytic effect of ascorbic acid on the enhancement of amperometry of dopamine exocytosis from single PC12 cells. CMACS conference (ACS), Cincinnati, Ohio, May 2000. Poster presentation
  • Yoshida M, Gratzl M: Novel optical and BioMEMS approaches to drug transport studies at Single Cancer Cells. Case Western Reserve University, BME Research Day, Cleveland, Ohio, March 2001. Poster presentation
  • Oruganti P, Gratzl M: Electrochemical sensing in restricted biological domains: an experimental and theoretical study. Case Western Reserve University, BME Research Day, Cleveland, Ohio, March 2001. Poster presentation
  • Thesfayesus W, Gratzl M: Development of a flexible two-electrode potentiostat for biomedical applications. BME Research Day, Case Western Reserve University, Cleveland, Ohio, March 2001. Poster presentation
  • Gratzl M: Microvoltammetry for applications at single cell level biomedical studies. ECS Annual Meeting, Washington, DC, March 2001. Invited talk
  • Gratzl M: Microvoltammetry for drug transport studies at single cancer cells. CUNY Queens College, New York, April 2001. Invited seminar
  • Gratzl M: Electrochemistry and optical detection in microscopic domains, and applications for studies at single cancer cells. ICAS International Conference on Analytical Sciences, Tokyo, Japan, August 2001. Invited talk
  • Gratzl M: Dynamic cellular transport at BioMEMS. MUACC, Univ. of Pittsburgh, October 2002. Invited talk
  • Tohda K, Yang J, Yoshida M, Gratzl M: Sliver sensor for in vivo metabolic monitoring. FACSS, Providence, RI, October 2002. Invited talk
  • Gratzl M: Electrochemical and optical microsensing in vitro and in vivo. International Conference on Electrochemical Sensors, Matrafured, Hungary, October 2002. Invited 40-min keynote lecture to the entire conference
  • Gratzl M: Ionophores and shape recognition. Cleveland State University, Cleveland, Ohio, October 2002. Invited seminar
  • Gratzl M, Nair S, Kashyap R: Mathematical shape recognition for assessing cellular transport with chemical microsensors. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2003. Invited keynote lecture
  • Nair S, Gratzl M: Assessing cellular transport at live cells with ion-selective ultramicroelectrodes. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2003. Oral presentation
  • Tohda K, Gratzl M: Sliver type autonomous optical sensors for in vivo monitoring of glucose and electrolytes. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2003
  • Gratzl M: Biomedical microsensing and “shape based” data analysis for research and clinical applications. U. of Tennessee and U. of Memphis, Dept. of BME, Memphis, Tennessee, February 2003. Invited seminar
  • Tohda K, Gratzl M: In vivo glucose sensing. Case Western Reserve University, SHOWCASE, Cleveland, Ohio, April 2003. Poster presentation
  • Yoshida M, Tohda K, Gratzl M: Device for precise reagent delivery and solution preparation. Case Western Reserve University, SHOWCASE, Cleveland, Ohio, April 2003. Poster presentation
  • Gratzl M: BioMEMS platform for assessing cellular transport. Zhejian University, Center for Biomedical Engineering, Hangzhou, China, April 2003. Invited seminar
  • Gratzl M, Nair S, Tohda K: Microminiature optical monitor for continuous in vivo glucose diagnostics. Biomedical Engineering Society Fall meeting, Nashville, Tennessee, October 2003. Oral presentation
  • Nair S, Gratzl M: Mathematical shape recognition for assessing cellular transport with chemical microsensors. Biomedical Engineering Society Fall meeting, Nashville, Tennessee, October 2003. Poster presentation
  • Shetty G, Tohda K, Gratzl M: Rotating sample system (RSS) for blood and body fluid diagnostics. Biomedical Engineering Society Fall meeting, Nashville, Tennessee, October 2003. Oral presentation
  • Tohda K, Gratzl M: Design and testing of a microminiature implantable sensing array for glucose and electrolytes. Diabetes Technology Meeting, San Francisco, California, November 2003. Poster presentation
  • Gratzl M: Sensing of ions, metabolites, and drug molecules in vitro and in vivo. Medtronic, Minneapolis, Minnesota, December 2003. Invited seminar
  • Gratzl M, Nair S, Tohda K: Optical telemetry of glucose and electrolytes across the skin from an implanted microscopic multicolor bar. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2004. Invited keynote lecture
  • Yoshida M, Gratzl M: Rapid cell pattern formation on BiomEMS chips by using hydrodynamic manipulation. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2004. Oral presentation
  • Shetty G, Tohda K, Gratzl M: Rotating sample system (RSS) for trace metal analysis. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2004. Oral presentation
  • Tohda K, Gratzl M: Microminature optode-based implantable sensing array for glucose and electrolytes. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2004. Invited talk
  • Gratzl M: Optical telemetry of ions and metabolites from the sliver sensor across the skin. Bayer Health Care, Elkhart, Indiana, April 2004. Invited seminar
  • Gratzl M, Tohda K, Nair S: Microminature, continuous, optical monitor for glucose and electrolytes for astronauts. ASMA meeting, Anchorage, Alaska, May 2004. Poster presentation
  • Tohda K, Gratzl M: Microminiature monitor for vital electrolyte and metabolite levels of astronauts. Strategic research to enable NASA’s exploration missions. Cleveland, Ohio, June 2004. Invited talk
  • Tohda K, Kim Y, Gratzl M: Microminiature optode-based implantable sensor array for glucose and electrolytes. Great Lakes photonics symposium, Aerospace/NASA applications conference, Biomedical optics for astronautics. Cleveland, Ohio, June 2004. Oral presentation
  • Gratzl M, Nair S, Tohda K: Optical telemetry across the skin using an implantable multicolor bar. Great Lakes photonics symposium, Aerospace/NASA applications conference, Biomedical optics for astronautics. Cleveland, Ohio, June 2004. Invited talk
  • Gratzl M: Electrochemical and optical detection in microscopic domains. Biological applications. Euroanalysis XIII, Salamanca, Spain, August 2004. Invited keynote lecture (40 min lecture given to the entire congress)
  • Shetty G, Gratzl M: Novel technology platform for detection of trace metals in microliter biomedical samples. Biomedical Engineering Society Fall meeting, Philadelphia, Pennsylvania, October 2004. Oral presentation
  • Suresh G, Gratzl M: Monitoring neurotransmitter release from single live cells using BiomEMS. Biomedical Engineering Society Fall Meeting, Philadelphia, Pennsylvania, October 2004. Poster presentation                                                                             
  • Shetty G, Gratzl M: Rotating sample system: a simple equivalent of the rotating disk electrode for detection of trace Pb in microliter samples. Electrochemical Society Meeting, Honolulu, Hawaii, October 2004. Oral presentation
  • Gratzl M: Development of a microminiature multisensing bar for in vivo monitoring of glucose and electrolytes. Becton-Dickinson, Raleigh, North Carolina, November 2004. Invited seminar
  • Gratzl M: Sliver sensor for monitoring ions and metabolites in vivo with optical telemetry. Department of Genetics, Case Western Reserve University, Cleveland, Ohio, January 2005. Invited seminar
  • Gratzl M, Tohda K: Sliver sensor for monitoring ions and metabolites in vivo with optical telemetry. Department of Genetics, Case Western Reserve University, seminar series on Metabolic Syndrome X, Cleveland, Ohio, January 2005. Invited seminar
  • Tohda K, Gratzl M: Sliver sensor: an ionophore based optical sensor array for glucose and electrolytes. Pittsburgh Conference on Analytical Chemistry, February 2005, Orlando Florida. Invited keynote lecture
  • Nair S, Gratzl M, Tohda K: Sliver sensor: three-color processing of optical information for in vivo metabolic monitoring. Pittsburgh Conference on Analytical Chemistry, February 2005, Orlando Florida. Invited talk
  • Kao LTH, Hsu HY, Shetty G, Gratzl M: Electrochemical pH-stat for enzyme activity measurements in micro-liter biological samples. BME Research Day, Case Western Reserve University, Cleveland, Ohio, March 2005. Poster presentation
  • Shetty G, Gratzl M: Rotating sample system: rheological modulation of hydrodynamic electrochemistry by biomolecules. Case Western Reserve University, ShowCASE, Cleveland, Ohio, April 2005. Poster presentation
  • Gratzl M, Nair S, Kashyap R, Lu H, Yi C: Electrochemical microtechniques for assessing cellular transport. International Conference on Bio-electrochemistry. Joint Meeting Bioelectrochemistry/ISE, Coimbra, Portugal, June 2005. Invited keynote lecture (40 min talk given to the entire congress)
  • Gratzl M, Tohda K: Microsensing for biomedical applications. Guidant Co., Minneapolis, Minnesota, September 2005. Invited seminar
  • Tohda K. Gratzl M: Optode evaluation for cardiac applications. Guidant Co., Minneapolis, Minnesota, September 2005. Invited seminar
  • Kao L, Hsu S, Shetty G, Gratzl M: Electrochemical pH-stat for enzyme activity measurements in micro-liter biological samples. BME Research Day, Case Western Reserve University, Cleveland, Ohio, October 2005. Poster presentation
  • Shetty G, Gratzl M: Rotating Sample System: rheological modulation of hydrodynamic electrochemistry by biomolecules. Frontiers in electrochemical science and technology, Yeager Center of Electrochemical Science International Symposium, Case Western Reserve University, Cleveland, Ohio, October 2005. Poster presentation
  • Gratzl M: Micro-electrochemistry for biomedical applications. First E.B. Yeager Frontiers in Electrochemical Science and Technology International Conference, Cleveland, Ohio, October 2005. Plenary lecture
  • Gratzl M: Micro-electrochemistry for micro biomedical applications. International conference on electrochemical sensors. To International Conference on Electrochemical Sensors, Matrafured, Hungary, November 2005. Invited 40-min keynote lecture to the entire conference
  • Gratzl M, Nair S, Tohda K: Ionophore based sliver sensor for multivariable optical monitoring. Pittsburgh Conference, Chicago, March 2006. Invited keynote lecture
  • Driever C, Tohda K, Gratzl M: Microminature, autonomous optical sensor array for monitoring ions and metabolites. SOURCE symposium, Case Western Reserve University, Cleveland, Ohio, April 2006. Poster presentation.
  • Gratzl M: Optode technology for monitoring (bio)chemicals in vitro and in vivo. Biophotonics conference at Great Lakes photonics symposium. Dayton, Ohio. June 2006. Invited talk
  • Kao L, Hsu S, Shetty G, Gratzl M: Electrochemical pH-stat for microliter fluid specimens. ECS meeting. Cancun, Mexico. September 2006. Oral presentation
  • Gratzl M, Nair S, Kashyap R, Hopfer U: Secretion of ions during stimulated release of mucins from granular structures in epithelia cells: new insight obtained using ion-selective electrodes. Pittsburgh Conference on Analytical Chemistry. Organized Contributed Session – Ionophore-Based Chemical Sensors. Chicago, Illinois, March 2007. Invited keynote lecture
  • Sheth D, Gratzl M: MEMS electrode array to monitor molecular transport of oxygen at single cells and small cell clusters. Yeager Center – Electrochemical Society meeting, Cleveland, Ohio, June 2007. Oral presentation
  • Nair S, Rice L, McCandless S, Gratzl M: Sliver sensor for minimally invasive optical monitoring of glucose and electrolytes in the dermis. Diabetes Technology Meeting, San Francisco, California, October 2007. Poster presentation
  • Sheth D, Suresh G, Yang J, Ladas T, Gratzl M: BioMEMS microelectrode array to monitor molecular transport at multiple single cells and small cell clusters in parallel. Annual Fall Meeting of the Biomedical Engineering Society, Salt Lake City, Utah, November 2007. Oral presentation
  • Gratzl M: Micro-electrochemistry for enzyme and cellular transport studies. Surface Modification for Chemical and Biochemical Sensing International Workshop, Warsaw, Poland, October 2007. Invited keynote lecture
  • Gratzl M: Physical chemistry in microscopic domains and applications for studies on single cancer cells. Ǻbo Akademi, Turku, Finland, November 2007. Invited seminar
  • Nair S, Gratzl M: New picture of ionic secretion from epithelial cells obtained in vitro using ion-selective electrodes and quantitative mass transport reconstruction. Pittsburgh Conference on Analytical Chemistry. Organized Contributed Session – Ionophore-Based Chemical Sensors. New Orleans, Louisiana, March 2008. Invited keynote lecture
  • Nair S, Gratzl M: In vivo testing of the ionophore-based sliver sensor for real-time monitoring of metabolic status. Pittsburgh Conference on Analytical Chemistry. Organized Contributed Session – Ionophore-Based Chemical Sensors, New Orleans, Louisiana, March 2008. Poster presentation
  • Nair S, Rice L, Tohda K, McCandless S, Gratzl M: Sliver sensor, a minimally invasive metabolic monitoring device. ShowCASE, Case Western Reserve University, Cleveland, Ohio, March 2008. Poster presentation
  • Above presented also at: BME Research Day, Case Western Reserve University, Cleveland, Ohio, March 2008. Poster presentation
  • Kao LT, Gratzl M: Reagentles pH-stat for body fluid diagnostics in microliter specimens. ShowCASE, Case Western Reserve University, Cleveland, Ohio, March 2008. Poster presentation
  • Above presented also at: BME Research Day, Case Western Reserve University, Cleveland, Ohio, March 2008. Poster presentation
  • Sheth D, Suresh G, Yang J, Zorman C, Gratzl M: MEMS devices for parallel experimentation on single cells and small cell clusters to rapidly obtain biostatistical data. ShowCASE, Case Western Reserve University, Cleveland, Ohio, March 2008.
  • Above presented also at: BME Research Day, Case Western Reserve University, Cleveland, Ohio, March 2008. Poster presentation
  • Kao LT, Gratzl M: Electrochemical micro pH-stat for the measurement of enzyme activities in microliter samples. Yeager Center – Electrochemical Society meeting, Cleveland, Ohio, May 2008. Poster presentation
  • Sheth D, Suresh G, Yang J, Zorman C,  Gratzl M: Electrochemical BioMEMS for cellular transport studies. Yeager Center – Electrochemical Society meeting, Cleveland, Ohio, May 2008. Poster presentation
  • Nair S, Gratzl M: Ionophore – chromoionophore based optical sensing device for in vivo metabolic monitoring. Yeager Center – Electrochemical Society meeting, Cleveland, Ohio, May 2008. Poster presentation
  • Gratzl M: Alternate current scanning electrochemical microscopy for obtaining chemical information. Ruhr-Universität, Lehrstuhl für Analytische Chemie, Laboratorium für Sensorik, Bochum, Nord-Rhein Westphalen, Germany, July 2008. Invited seminar
  • Gratzl M: New picture of electrolyte and mucus secretion from epithelial cell derived from dynamic recordings at cell monolayers with ISEs. 5th Workshop on Scanning Electrochemical Microscopy. Blue Mountain Lake, New York, August 2008. Invited keynote lecture
  • Gratzl M: Biomedical sensing on the very small to microscopic scale. Michigan Technological University, Department of Biomedical Engineering. Houghton, MIichigan, September 2008. Invited seminar
  • Gratzl M: Biomedical sensing on the very small to microscopic scale. Case Western Reserve University, Department of Biomedical Engineering. Cleveland, OH, October 2008. Seminar
  • Shetty G, Kao L, Sheth D, Tohda K, Gratzl M: Hydrodynamic electrochemistry in microliter samples. Matrafured, 2008: International Conference on Electrochemical Sensors. Dobogokö, Hungary, October 2008. Invited 40-min keynote lecture to the entire conference
  • Hardesty R, Sheth D, Suresh G, Yang J, Zorman C, Gratzl M: BioMEMS microelectrode array to monitor molecular transport at multiple single cells and small cell clusters in parallel. Annual Fall Meeting of the Biomedical Engineering Society, Saint Louis, MS, October 2008. Poster presentation
  • Shah A, Nair S, Gratzl M: Functionality studies of an optical metabolic monitor in serum. Annual Fall Meeting of the Biomedical Engineering Society. Saint Louis, Missouri, October 2008. Poster presentation
  • Gratzl M: MEMS platform for measuring drug transport together with other parameters such as oxygen in cancer spheroids. The Cleveland Clinic Foundation, Taussig Cancer Center, Cleveland, Ohio, November 2008. Invited seminar
  • PhD, MS, and BS students in the Laboratory for Biomedical Sensing at BME, and Gratzl M: Electrochemical and optical microsensing in biomedical research and diagnostics in vitro and in vivo. Case Electrochemistry Forum, Case Western Reserve University, Yeager Center and the Electrochemical Society, Cleveland, Ohio, February 2009. Talks and poster presentations
  • Gratzl M: Biomedical sensors, systems, and simulation. BME Open House, Case Western Reserve University, Cleveland, OH, February 2009. Oral presentation on BME research on one of four major areas of research at BME
  • Oruganti P, Gratzl M: Real-time observation of the movement and distribution of anticancer drug molecules in single cancer cells. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Oral presentation
  • Nair S, Ricel L, McCandless S, Gratzl M: Testing the optode based sliver sensor in vitro and in vivo for metabolic monitoring in small laboratory animals. Pittsburgh Conference on Analytical Chemistry, Organized Contributed Session – Ionophore-Based Chemical Sensors, Chicago, Illinois, March 2009. Invited keynote lecture
  • Kao LT, Gratzl M: Reagent-free micro pH-stat for rapid enzyme assays in body fluids. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Oral presentation
  • Shetty G, Kao LT, Tohda K, Gratzl M: Hydrodynamic electrochemistry in microliter samples. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Oral presentation
  • Sheth D, Diefes R, Gratzl M: 2D electrode design for measuring 3D averaged concentration in a 1µL size inhomogeneous sample without sample stirring. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Poster presentation
  • Ahuja P, Nair G, Gratzl M: Characterization of optode beads for in vivo metabolic monitoring. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Poster presentation
  • Hardesty R, Sheth D, Zorman C, Grazl M: BioMEMS platform for monitoring drug penetration in 3D multicellular tumor spheroids. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2009. Poster presentation
  • Sheth D, Diefes R, Gratzl M: Spatially averaging electrodes. Annual Meeting of the American Chemical Society, Organized Session Honoring Prof. J. Janata. San Francisco, California, May 2009. Invited talk
  • Sheth D, Gratzl M: Spatially averaging electrodes. ACS (CERMAC) meeting, Cleveland, Ohio, May 2009. Oral presentation
  • Oruganti P, Gratzl M: Sustained dosing of molecules into cells to elucidate cellular function. ACS (CERMAC) meeting, Cleveland, Ohio, May 2009. Oral presentation
  • Oruganti P, Gratzl M: Distribution of anticancer drug molecules in single cells during direct intracellular dosing. Biomedical Graduate Student Symposium, SOM, Case Western Reserve University, Cleveland, Ohio, May 2009. Poster presentation
  • Hardesty R, Sheth D, Gratzl M: BioMEMS platform to measure changes in oxygen metabolism of single sensitive and resstance MCF-7 breast cancer cells under the influence of doxorubicin. Biomedical Engineering Society Fall Meeting, Pittsburgh, Pennsylvania, October 2009. Poster presentation
  • Oruganti P, Gratzl M: Binding and distribution of doxorubicin in MCF-7 breast cancer cells during sustained intracellular dosing. Biomedical Engineering Society Fall Meeting, Pittsburgh, Pennsylvania, October 2009. Poster presentation
  • Gratzl M: Chemical sensing at cell constructs and in preclinical trials in animals. Universita degli Studi di Firenze, Italy, November 2009. Invited seminar
  • Ahuja P, Nair S, Pähler M, Schuhmann W, Gratzl M: Optode-based high-resolution chemical imaging of 2D surfaces. Pittsburgh Conference on Analytical Chemistry, Organized session on ionophore-based sensors, Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Invited keynote lecture
  • Peshkova M, Ahuja P, Nair S, Gratzl M: Optode microarray for in vitro diagnostics in microliter drops of serum and whole blood. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Oral presentation
  • Sheth D, Hardesty R, Gratzl M: Multiparametric BioMEMS platform to simultaneously study drug efflux and resulting oxygen consumption from single resistant cancer cells. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Oral presentation
  • Oruganti P, Gratzl M: Titration of indicator dyes and drug molecules within single cancer cells. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Oral presentation
  • Oruganti P, Wang D, Mohan N, Gratzl M: Optical measurement of drug penetration in cancer tumor spheroids.  Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Oral presentation
  • Nair S, Rice L, McCandless S, Gratzl M: Long-term functionality of the sliver sensor in vitro in serum and in vivo in the skin of mice for monitoring diabetes related parameters. Pittsburgh Conference on Analytical Chemistry, Orlando, Florida, March 2010. Oral presentation
  • Sheth D, Gratzl M: Microelectrode platform for assessing the interrelationship between oxygenation status and drug efficacy in multicellular tumor spheroids. Case Comprehensive Cancer Center, June 2010. Poster presentation
  • Ahuja P, Nair S, Gratzl M: Current and future glucose monitoring techniques. Am. Assoc. Clin. Chem., Anaheim, July 2010. Symposium proposed and organized by Punkaj Ahuja and Sumitha Nair; the keynote lecture was given by Punkaj Ahuja; he also chaired and moderated the symposium.
  • Ahuja P, Nair S, Gratzl M: Optode-based high-resolution chemical imaging of 2D surfaces. Biomedical Engineering Society Fall Meeting, Austin, October 2010. Poster presentation
  • Pähler M, Gratzl M, Schumann W: Local chloride detection and simultaneous distance measurement in SECM combined with impedance spectroscopy. Electrochemistry 2010: from microscopic understanding to global impact. Bochum, Germany, September 2010. Oral presentation
  • Gratzl M: Real-time monitoring of transport of biomolecules and therapeutics at single cells, monolayers, and 3D tumor constructs. Case Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, October 2010. Seminar
  • Sheth D, Oruganti P, Wang D, Nair S, Gratzl M: Biochemical sensing at in vitro cell constructs. PACIFICHEM, Honolulu, December 2010. Invited keynote lecture
  • Gratzl M: Biomedical sensing for diagnostic applications and basic research. Case Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, February 2011. Seminar
  • Sheth D, Wang D, Oruganti P, Nair S, Gratzl M: Dynamic distribution maps of acidity and hypoxia within multicellular tumor spheroids obtained with optode microbeads and a MEMS microelectrode array. Pittsburgh Conference on Analytical Chemistry, Atlanta, Georgia, March 2011. Invited keynote lecture
  • Ahuja P, Peshkova M, Hemphill B, Gratzl M: Multiparametric diagnostic slide for point-of-care testing of metabolic profiles in the ICU. Pittsburgh Conference on Analytical Chemistry, Atlanta, Georgia, March 2011. Oral presentation
  • Rebec M, Brodskiy I, Gratzl M: Testing Chloride with diffusional microtitration as a part of Cystic Fibrosis test. Pittsburgh Conference on Analytical Chemistry, Atlanta, Georgia, March 2011. Poster presentation
  • Stanton J, Sheth D, Zorman C, Gratzl M: Microfabricated pH-stat slide for reagentless and calibration-free determination of enzyme markers in clinical samples. Pittsburgh Conference on Analytical Chemistry, Atlanta, March 2011. Oral presentation
  • Hemphill B, Gratzl M: Light emitting diodes and a monochrome detector to measure chromoionophore response in optode-based chemical sensors. Pittsburgh Conference on Analytical Chemistry, Atlanta, March 2011. Oral presentation
  • Ahuja P, Nair S, Gratzl M: Optode-bead-based dynamic chemical imaging of 2D surfaces. Pittsburgh Conference on Analytical Chemistry, Atlanta, March 2011. Poster presentation
  • Nair S, Rice L, McCandless S, Rebec M, Gratzl M: Continuous monitoring of metabolic status with the sliver sensor in mice. Pittsburgh Conference on Analytical Chemistry, Atlanta, March 2011. Oral presentation
  • Sheth D, Zorman C, Gratzl M: MEMS multielectrode platform for assessing the interrelationship between oxygenation status and drug efficacy in multicellular tumor spheroids. Pittsburgh Conference on Analytical Chemistry, Atlanta, March 2011. Oral presentation
  • Sheth D, Ahuja P, Peshkova M, Gratzl M: Oxygen consumption by cells and ensuing acidification in 3D tissue-like constructs monitored with microvoltammetry and high-resolution optode-based imaging. Matrafured International Conference on Electrochemical Sensors, Dobogokö, Hungary, June 2011. Invited 40-min keynote lecture
  • Gratzl M: Technology that could be used to support drug development. Case Comprehensive Cancer Center, Developmental Therapeutics, September 2011. Invited talk
  • Nair S, Hopfer U, Gratzl M: New understanding of the dynamics of ion and mucus secretion from tight epithelial monolayers derived from ISE measurements and mathematical flux reconstruction. METROMED, Saint-Petersburg, Russia, November 2011. Invited keynote lecture
  • Rebec M, Nair S, Gratzl M: Sliver Sensor: an Optical Sensing Array for in-vivo Monitoring of Metabolic Status in Diabetics. MetroMed 2011, Saint-Petersburg, Russia, November 12, 2011. Oral presentation
  • Gratzl M: Biomedical sensing under hydrodynamic conditions and on the micron scale I. Saint-Petersburg State University, Faculty of Applied Mathematics, Saint-Petersburg, Russia, December 6, 2011. Invited seminar
  • Gratzl M: Biomedical sensing under hydrodynamic conditions and on the micron scale II. Saint-Petersburg State University, Faculty of Applied Mathematics, Saint-Petersburg, Russia, December 11, 2011. Invited seminar
  • Ahuja P, Peshkova M, Hemphill B, Sheth D, Gratzl M: Multi-parameter slide for the point-of-care testing of metabolic profiles in the ICU: a new platform for laboratory diagnostics. Biomedical Graduate Student Symposium, School of Medicine, Case Western Reserve University, Cleveland, Ohio, May 2012. Poster presentation.
  • Ahuja P, Peshkova M, Gratzl M: Multi-parameter slide for the point-of-care testing of metabolic profiles in the ICU: A new platform for diagnostics. American Analytical Chemical Society, Los Angeles, California, March 2012. Student poster competition.
  • Gratzl M: New directions in biomedical sensing. Case Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, March 2012. Seminar
  • Ahuja P, Nair S, Narayan S, Gratzl M: Optochemical imaging of functionally active surfaces. Biomedical Engineering Society Fall meeting, Atlanta, Georgia, October 2012. Poster presentation
  • Ahuja P, Peshkova M, Yu J, Gratzl M: Optical slide for point-of-care testing of metabolic profiles in the ICU: a new, versatile platform for low-cost diagnostics. Biomedical Engineering Society Fall Meeting, Atlanta, Georgia, October 2012. Oral presentation
  • Lee K, Hubbard L, Gratzl M, Steinmetz N: Comparison of icosahedron and rod-shaped viral nanoparticles in a spheroid tumor model. Physical Virology Gordon Research Conference. January 2013, Ventura. Poster presentation
  • Ahuja P, Peshkova M, Hemphill B, Gratzl M: Multi-parameter slide for the point-of-care testing of metabolic profiles in the ICU: a new platform for laboratory diagnostics. IEEE-EMBS Special Topic Conference on Point-of-Care Healthcare Technologies, Bangalore, India, January 2013. Poster presentation
  • Hubbard L, Lee K, Steinmetz N, Ahuja P, Gratzl M: Micro-electrochemical sensing and confocal microscopy show very different delivery of classical and  nanocarrier bound drug molecules in the conventional “inside-out” tissue model relative to a novel “inside-in” model. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Invited keynote lecture
  • Rebec S, Gratzl M: Reconstruction of color of optically active sensing wells from underneath the skin. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Poster presentation
  • Ahuja P, Hemphill B, Ustin J, Gratzl M: Clinical measurements with an optical multisensor array in point-of-care settings. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Oral presentation
  • Oruganti P, Yoshida M, Gratzl M: Laboratory solution preparation using hydrodynamic impedance and diffusional resistance. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. E-poster presentation
  • Hubbard L, Lee K, Steinmetz N, Gratzl M: Fluorescence measurement of the penetration of nano-carrier bound drug molecules into model tissue. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Poster presentation
  • Miszuk J, Ahuja P, Gratzl M: Optochemical imaging of functionally active surfaces. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Oral presentation
  • Ahuja P, Vantassell F, Peshkova M, Gratzl M: Optode based imaging of pH across a multicellular model tissue. Pittsburgh Conference on Analytical Chemistry, Philadelphia, Pennsylvania, March 2013. Oral presentation
  • Sheth D, Gratzl M: Differential linear scan microvoltammetry for measurements in biological environments. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2014. Invited keynote presentation
  • Rebec S, Gratzl M: Reconstruction of color of miniature optode-based sensing wells from under semi-transparent layers with absorption and scattering properties modeling the skin. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2014. Oral presentation
  • Kim K, Gratzl M: Capillary model for drug penetration into the tumor tissue with integrated microsensors for monitoring hypoxia, acidification, and the evolving concentration profile of the drug inside the model tissue. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2014. Poster presentation
  • Ahuja P, Ustin J, Gratzl M: Pilot clinical trial of an optode-array-based point-of-care metabolic tester slide. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2014. Poster presentation
  • Rebec M, Cserfalvi T, Rebec M, Gratzl M: Point-of-care sweat chloride tester for cystic fibrosis screening in newborns in 5 microliters of sweat. Pittsburgh Conference on Analytical Chemistry, Chicago, Illinois, March 2014. Poster presentation
  • Gratzl M: Experimental approaches to study drug transport at individual cancer cells and in multicellular environment in vitro. Part I.  Individual cancer cells. Saint Petersburg State University, Faculty of Chemistry, Saint Petersburg, Russia, March 2014. Invited teaching lecture
  • Gratzl M: Experimental approaches to study drug transport at individual cancer cells and in multicellular environment in vitro. Part II. 3D multicellular constructs. Saint Petersburg State University, Faculty of Chemistry, Saint Petersburg, Russia, March 2014. Invited teaching lecture
  • Gratzl M: Optochemical and electrochemical methods for biomedical measurements. Saint Petersburg State University, Department of Physical Chemistry, Saint Petersburg, Russia, March 2014. Invited seminar
  • Gratzl M: Electrochemical sensing methodologies for the elucidation of biological transport processes. 225th ECS (Electrochemical Society) meeting, Richard P Buck Memorial Session, Orlando, Florida, May 2014. Invited talk
  • Gratzl M, Sheth D: Differential Linear Scan Voltammetry: Analytical performance in comparison with pulsed voltammetry techniques. 65th Annual Meeting of the International Society of Electrochemistry, Lausanne, Switzerland, August 2014. Oral presentation
  • Gratzl M, Oruganti P, Wang D, Sheth D, Kim K: Multicellular tumor spheroids for high-throughput drug screening and personalized medicine. Lubrizol Advanced Materials, Brecksville, Ohio, March 2015. Invited seminar
  • Gratzl M: Drug penetration in a hemi-spherical in vitro model of tumor tissue. Department of Biomedical Engineering, CWRU. February 2015. Oral presentation
  • Gratzl M: Need for 3D multicellular tumor models. Department of Radiology and Pathology, University Hospitals, Cleveland, Ohio. November 2015. Invited seminar