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Three BME Projects Land I-Corps@Ohio Funding

I-Corps@Ohio recently awarded funding to three projects led by faculty at Case Western Reserve University’s Department of Biomedical Engineering. Modeled after the National Science Foundation’s I-Corps program, the main goal of the statewide grant-funded program is to accelerate commercialization of technologies developed at Ohio universities. The Case BME projects selected for the program were:

Biomimetic, antioxidative coatings for neural implants – A team led by Jeffrey Capadona, Ph.D., has developed a coating technology for medical devices aimed at mitigating deleterious oxidative stress events that lead to device failure. Through the I-Corps@Ohio program, the team hopes to develop a platform for applying this coating to a variety of neural implants to improve functionality and increase long-term device stability. BME graduate student Griffin Rial, and Post-doc Andrew Shoffstall are co-entrepreneurial leads on the project.

An enzyme biomarker analyzer – Miklos Gratzl, Ph.D., serves as principal investigator on a project aimed at commercialization of proprietary intellectual property for measuring nearly 50 percent of all clinically-important enzyme markers in point-of-care settings using disposable slides and one device. His team in the Laboratory for Biomedical Sensing has created an enzyme biomarker analyzer based on micro-pH-stating for point-of-care diagnostics of many acute diseases and chronic conditions.  Zhehao Zhang, a graduate student in BME, is entrepreneurial lead on the project.

Computational Scalpel™ – A team led by Satish Viswanath, Ph.D., has developed a patented machine learning-based surgical planning tool for use by colorectal surgeons. The technology constructs a precise "GPS"-style surgical margin plan that provides a high-resolution, interactive visualization of tumor extent in vivo on rectal MRIs. This will allow colorectal surgeons to plan procedures to be as minimally invasive as possible while improving patient outcomes and reducing recurrence rates. Jacob Antunes, a graduate student in BME, serves as entrepreneurial lead.