Prostatome: a combined anatomical and disease based MRI atlas of the prostate.

TitleProstatome: a combined anatomical and disease based MRI atlas of the prostate.
Publication TypeJournal Article
Year of Publication2014
AuthorsRusu, M, Bloch NB, Jaffe CC, Genega EM, Lenkinski RE, Rofsky NM, Feleppa E, Madabhushi A
JournalMedical physics
Date Published2014 Jul

In this work, the authors introduce a novel framework, the anatomically constrained registration (AnCoR) scheme and apply it to create a fused anatomic-disease atlas of the prostate which the authors refer to as the prostatome. The prostatome combines a MRI based anatomic and a histology based disease atlas. Statistical imaging atlases allow for the integration of information across multiple scales and imaging modalities into a single canonical representation, in turn enabling a fused anatomical-disease representation which may facilitate the characterization of disease appearance relative to anatomic structures. While statistical atlases have been extensively developed and studied for the brain, approaches that have attempted to combine pathology and imaging data for study of prostate pathology are not extant. This works seeks to address this gap.

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Alternate JournalMed Phys

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